RNA interference (RNAi) is a promising gene regulatory approach in functional genomics
that has significant impact on crop improvement which permits down-regulation in gene …

The study of gene function in filamentous fungi is a field of research that has made great
advances in very recent years. A number of transformation and gene manipulation strategies …

Mitochondrial DNA (mtDNA) mutations are an important cause of human disease for which
there is no efficient treatment. Our aim was to determine whether the A8344G mitochondrial …

Background Both viral and nonviral carriers have been used to carry small interfering RNA
molecules (siRNA) to their cytosolic mRNA target. To date, few peptide carriers have been …

The use of antisense oligonucleotides as therapeutic agents has generated considerable
enthusiasm in the research and medical community. Antisense oligonucleotides as …

Since double-stranded RNA (dsRNA) has not until recently generally been thought to be
deliberately expressed in cells, it has commonly been assumed that the major source of …

The neuropeptide galanin has been implicated in inhibiting seizures and protecting
hippocampal neurons from excitotoxic injury. In the hippocampus galanin acts through two …

[Frontiers in Bioscience 11, 89-112, January 1, 2006] 89 HIV-1 inactivation by nucleic acid
aptamers Daniel M. Held 1, 3, Jay D. Page 1 [Frontiers in Bioscience 11, 89-112, January 1 …

Experimental RNA interference (RNAi) leading to the selective knockdown of gene function
is induced by introducing into cells either double stranded RNA (dsRNA), or short interfering …

Subarachnoid hemorrhage (SAH), mostly caused by aneurysm rupture, is a pathological
condition associated with oxidative stress and neuroinflammation. Toll‐like receptors (TLRs) …