The role of non-coding RNAs in oncology
FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications
AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
M Xu, X Chen, K Lin, K Zeng, X Liu, X Xu, B Pan… - Journal of hematology & …, 2019 - Springer
Background Abnormal expression of long non-coding RNAs (lncRNAs) has been found in
almost all human tumors, providing numerous potential diagnostic biomarkers, prognostic …
almost all human tumors, providing numerous potential diagnostic biomarkers, prognostic …
MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy
F Jin, Y Wang, M Li, Y Zhu, H Liang, C Wang… - Cell death & …, 2018 - nature.com
Hepatocellular carcinoma (HCC) generally possesses a high resistance to chemotherapy.
Given that autophagy is an important factor promoting tumor chemoresistance and HCC …
Given that autophagy is an important factor promoting tumor chemoresistance and HCC …
HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation
High mobility group A1 (HMGA1) chromatin regulators are upregulated in diverse tumors
where they portend adverse outcomes, although how they function in cancer remains …
where they portend adverse outcomes, although how they function in cancer remains …
Circulating microRNAs in acute and chronic exercise: more than mere biomarkers
RM Sapp, DD Shill, SM Roth… - Journal of Applied …, 2017 - journals.physiology.org
MicroRNAs (miRNAs) are short, noncoding RNAs that influence biological processes by
regulating gene expression after transcription. It was recently discovered that miRNAs are …
regulating gene expression after transcription. It was recently discovered that miRNAs are …
MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
L Cekaite, PW Eide, GE Lind, RI Skotheim… - Oncotarget, 2015 - pmc.ncbi.nlm.nih.gov
Gene expression is in part regulated by microRNAs (miRNAs). This review summarizes the
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …
miR-26 family and its target genes in tumorigenesis and development
C Li, Y Li, Y Lu, Z Niu, H Zhao, Y Peng, M Li - Critical Reviews in Oncology …, 2021 - Elsevier
The microRNA-26 family, including miR-26a, miR-26b, miR-1297 and miR-4465, is a group
of broadly conserved small RNAs with identical sequences at the seed region. The …
of broadly conserved small RNAs with identical sequences at the seed region. The …
miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19
Fat storage in adult mammals is a highly regulated process that involves the mobilization of
adipocyte progenitor cells (APCs) that differentiate to produce new adipocytes. Here we …
adipocyte progenitor cells (APCs) that differentiate to produce new adipocytes. Here we …
MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1
MiR-26 has emerged as a key tumour suppressor in various cancers. Accumulating
evidence supports that miR-26 regulates inflammation and tumourigenicity largely through …
evidence supports that miR-26 regulates inflammation and tumourigenicity largely through …