Introduction Severe thermal injury is characterized by profound morbidity and mortality.
Advances in burn and critical care, including early excision and grafting, aggressive …

The treatment of the emerging multidrug resistant (MDR) gram-negative organisms is a
challenge. The development of newer antibiotics has recently slowed down. This has led to …

The emergence of nosocomial infections due to multidrug-resistant Gram-negative bacteria
led to the revival of 'forgotten'antibiotics, such as polymyxins. Colistin, mainly colistimethate …

Emergence of multidrug-resistant Gram-negative nosocomial pathogens has led to
resurgence of colistin use. Safety and efficacy data regarding colistin use in pediatric …

Background: A rapid increase in multidrug-resistant Gram-negative infections has led to a
reemergence of colistin use globally. Although it is well described among adults, colistin use …

Studies about risk factors for mortality in burn children are scarce. We conducted this study
to evaluate the risk factors for mortality in pediatric burn patients. We included 110 patients …

Background: Nosocomial infection due to multidrug-resistant Gram-negative pathogens in
intensive care units is a challenge for clinicians and microbiologists, and has led to …

This article reviews mechanisms, incidences, risk factors and preventive modalities of
colistin toxicity as well as colistin use in special populations and through special routes. All …

Background: Colistin is active against most multidrug-resistant, aerobic Gram-negative
bacteria. Because of the reported nephrotoxicity during the first years of use of colistin, there …

Colistin is a venerable antibiotic whose fortunes have been revived by its excellent activity,
the diminishing output of novel clinically effective antibiotics and the increasing importance …