The genomic landscape of 2,023 colorectal cancers

AJ Cornish, AJ Gruber, B Kinnersley, D Chubb… - Nature, 2024 - nature.com
Colorectal carcinoma (CRC) is a common cause of mortality, but a comprehensive
description of its genomic landscape is lacking,,,,,,–. Here we perform whole-genome …

Mutation frequency and copy number alterations determine prognosis and metastatic tropism in 60,000 clinical cancer samples

N Calonaci, E Krasniqi, S Scalera, G Gandolfi, S Milite… - medRxiv, 2024 - medrxiv.org
The intricate interplay between somatic mutations and copy number alterations critically
influences tumour evolution and patient prognosis. Traditional genomic studies often …