The aryl hydrocarbon receptor (AHR) signaling pathway is a complex regulatory network
that plays a critical role in various biological processes, including cellular metabolism …

Background The transforming growth factor‐β (TGF‐β) pathway plays a pivotal role in
inducing epithelial‐mesenchymal transition (EMT), which is a key step in cancer invasion …

Bladder cancer (BC) has a 70% telomerase reverse transcriptase (TERT or hTERT in
humans) promoter mutation prevalence, commonly at− 124 base pairs, and this is …

Objective Helicobacter pylori (Hp) is a major risk factor for gastric cancer (GC). Hp promotes
DNA damage and proteasomal degradation of p53, the guardian of genome stability. Hp …

IL-17–producing Th17 cells are implicated in the pathogenesis of rheumatoid arthritis (RA)
and TNF-α, a proinflammatory cytokine in the rheumatoid joint, facilitates Th17 …

Abstract Syntaxin-6 (STX6), a protein of the syntaxin family, is located in the trans-Golgi
network and is involved in a variety of intracellular membrane transport events. STX6 is …

Background Gastric cancer (GC) is one of the most common malignancies, and an
increasing number of studies have shown that its pathogenesis is regulated by various …

The upstream stimulatory factor 2 (USF2) is a transcription factor implicated in several
cellular processes and among them, tumor development seems to stand out. However, the …

Abstract Rationale: Chitinase 3-like 1 (Chi3L1) protein is up-regulated in various diseases
including solid cancers. According to Genome-Wide Association Study (GWAS)/Online …

C-reactive protein (CRP) is a major acute phase protein and inflammatory marker, the
expression of which is largely liver specific and highly inducible. Enhancers are regulatory …