Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF
aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains …

Objective To characterize the accrual of long‐term disability in a cohort of actively treated
multiple sclerosis (MS) patients and to assess whether clinical and magnetic resonance …

Central nervous system B cells have several potential roles in multiple sclerosis (MS):
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …

Abstract Type I interferon (IFN-I) signalling represents a major target for modulation in a
virus' bid for latency. IFN-I perturbations are also present in such as Alzheimer's disease …

Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance
of circulating autoantibodies to pancreatic islets. However, almost nothing is known about …

Myelination is critical to normal functioning of the vertebrate nervous system. In
demyelinating diseases such as multiple sclerosis, oligodendrocytes, the myelinating cells …

The continuously prolonged human lifespan is accompanied by increase in
neurodegenerative diseases incidence, calling for the development of inexpensive blood …

A role for interferon (IFN) in systemic lupus erythematosus (SLE) pathogenesis is inferred
from the prominent IFN gene signature (IGS), but the major IFN species and its relationship …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system with a modest concordance rate in monozygotic twins, which strongly argues for …

Context: Klinefelter syndrome (KS) is the most common chromosome disorder in men (47,
XXY), exhibiting a phenotype with marked variation and increased morbidity. The …