This review focuses on the effects that ischemia and hypoxia have on the cerebral cortex
and the cerebellum during different periods of life. The acute interruption or reduction of …

Isolated brain tissue, especially brain slices, are valuable experimental tools for studying
neuronal function at the network, cellular, synaptic, and single channel levels …

The development of the living acute brain slice preparation for analyzing synaptic function
roughly a half century ago was a pivotal achievement that greatly influenced the landscape …

Axon outgrowth during development and neurotransmitter release depends on exocytotic
mechanisms, although what protein machinery is common to or differentiates these …

Although neurotransmitters are key substances closely related to evaluating degenerative
brain diseases as well as regulating essential functions in the body, many research efforts …

Inability to culture adult central neurons and the failure of injured neurons to regenerate in
the brain could be due to genetic controls or environmental inhibitors. We tested the …

Hippocampal slices have long been used to investigate properties of synaptic transmission
and plasticity. Here, for the first time, synapses in slices have been compared quantitatively …

Alcohol intoxication alters coordination and motor skills, and this is responsible for a
significant number of traffic accident-related deaths around the world. Although the precise …

Migraine with aura is a common but poorly understood sensory circuit disorder. Monogenic
models allow an opportunity to investigate its mechanisms, including spreading …

Hibernation in mammals is associated with a regulated depression of global cellular
functions accompanied by reductions of cerebral blood flow that would render the brain …