Copper and antibiotics: discovery, modes of action, and opportunities for medicinal applications

AG Dalecki, CL Crawford, F Wolschendorf - Advances in microbial …, 2017 - Elsevier
Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris

S Allert, D Schulz, P Kämmer, P Großmann, T Wolf… - Virulence, 2022 - Taylor & Francis
Candida species are a major cause of invasive fungal infections. While Candida albicans, C.
glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life …

[HTML][HTML] Role of divalent metals in infectious disease susceptibility and outcome

G Weiss, PL Carver - Clinical Microbiology and Infection, 2018 - Elsevier
Background Divalent metals play important roles in maintaining metabolism and cellular
growth of both eukaryotic hosts and invading microbes. Both metal deficiency and overload …

Emerging opportunities to manipulate metal trafficking for therapeutic benefit

EW Hunsaker, KJ Franz - Inorganic chemistry, 2019 - ACS Publications
The indispensable requirement for metals in life processes has led to the evolution of
sophisticated mechanisms that allow organisms to maintain dynamic equilibria of these ions …

The genome of opportunistic fungal pathogen Fusarium oxysporum carries a unique set of lineage-specific chromosomes

Y Zhang, H Yang, D Turra, S Zhou, DH Ayhan… - Communications …, 2020 - nature.com
Fusarium oxysporum is a cross-kingdom fungal pathogen that infects plants and humans.
Horizontally transferred lineage-specific (LS) chromosomes were reported to determine host …

Essential metals at the host–pathogen interface: nutritional immunity and micronutrient assimilation by human fungal pathogens

A Crawford, D Wilson - FEMS yeast research, 2015 - academic.oup.com
The ability of pathogenic microorganisms to assimilate sufficient nutrients for growth within
their hosts is a fundamental requirement for pathogenicity. However, certain trace nutrients …

Buried treasure: evolutionary perspectives on microbial iron piracy

MF Barber, NC Elde - Trends in Genetics, 2015 - cell.com
Host–pathogen interactions provide valuable systems for the study of evolutionary genetics
and natural selection. The sequestration of essential iron has emerged as a crucial innate …

A dormant microbial component in the development of preeclampsia

DB Kell, LC Kenny - Frontiers in medicine, 2016 - frontiersin.org
Preeclampsia (PE) is a complex, multisystem disorder that remains a leading cause of
morbidity and mortality in pregnancy. Four main classes of dysregulation accompany PE …

Intermicrobial interaction: Aspergillus fumigatus siderophores protect against competition by Pseudomonas aeruginosa

G Sass, SR Ansari, AM Dietl, E Déziel, H Haas… - PLoS …, 2019 - journals.plos.org
Pseudomonas aeruginosa and Aspergillus fumigatus are pathogens frequently co-
inhabiting immunocompromised patient airways, particularly in people with cystic fibrosis …