Oxidative stress and regulated cell death in Parkinson's disease

PA Dionísio, JD Amaral, CMP Rodrigues - Ageing research reviews, 2021 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Motor deficits usually associated with PD correlate with dopaminergic axonal …

Neurodegeneration and inflammation—an interesting interplay in Parkinson's disease

C Marogianni, M Sokratous, E Dardiotis… - International journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder, caused by, so far, unknown
pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated …

Global trends in the incidence, prevalence, and years lived with disability of Parkinson's disease in 204 countries/territories from 1990 to 2019

Z Ou, J Pan, S Tang, D Duan, D Yu, H Nong… - Frontiers in public …, 2021 - frontiersin.org
Background: Parkinson's disease (PD) is an increasing challenge to public health. Tracking
the temporal trends of PD burden would inform health strategies. Methods: Data of PD …

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

MA Nalls, C Blauwendraat, CL Vallerga… - The Lancet …, 2019 - thelancet.com
Background Genome-wide association studies (GWAS) in Parkinson's disease have
increased the scope of biological knowledge about the disease over the past decade. We …

[HTML][HTML] Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

ER Dorsey, A Elbaz, E Nichols, N Abbasi… - The Lancet …, 2018 - thelancet.com
Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's …

Prevalence of Parkinson's disease across North America

C Marras, JC Beck, JH Bower, E Roberts, B Ritz… - NPJ Parkinson's …, 2018 - nature.com
Estimates of the prevalence of Parkinson's disease in North America have varied widely and
many estimates are based on small numbers of cases and from small regional …

Parkinson's disease: Mechanisms, translational models and management strategies

C Raza, R Anjum - Life sciences, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …

The emerging evidence of the Parkinson pandemic

E Dorsey, T Sherer, MS Okun… - Journal of Parkinson's …, 2018 - content.iospress.com
Neurological disorders are now the leading source of disability globally, and the fastest
growing neurological disorder in the world is Parkinson disease. From 1990 to 2015, the …

The SH-SY5Y cell line in Parkinson's disease research: a systematic review

H Xicoy, B Wieringa, GJM Martens - Molecular neurodegeneration, 2017 - Springer
Parkinson's disease (PD) is a devastating and highly prevalent neurodegenerative disease
for which only symptomatic treatment is available. In order to develop a truly effective …

Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies

P Magalhães, HA Lashuel - npj Parkinson's Disease, 2022 - nature.com
Abstract Parkinson's disease (PD), the second most common progressive
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …