The role of antioxidants in the chemistry of oxidative stress: A review

AM Pisoschi, A Pop - European journal of medicinal chemistry, 2015 - Elsevier
Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …

N-Acetylcysteine (NAC): Impacts on Human Health

MCS Tenório, NG Graciliano, FA Moura, ACM Oliveira… - Antioxidants, 2021 - mdpi.com
N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

The chemistry and biological activities of N-acetylcysteine

Y Samuni, S Goldstein, OM Dean, M Berk - Biochimica et Biophysica Acta …, 2013 - Elsevier
BACKGROUND: N-acetylcysteine (NAC) has been in clinical practice for several decades. It
has been used as a mucolytic agent and for the treatment of numerous disorders including …

[HTML][HTML] Antioxidant therapy for treatment of inflammatory bowel disease: does it work?

FA Moura, KQ de Andrade, JCF Dos Santos… - Redox biology, 2015 - Elsevier
Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

Anthracycline‑induced cardiotoxicity in the chemotherapy treatment of breast cancer: Preventive strategies and treatment

F Cai, MAF Luis, X Lin, M Wang… - Molecular and …, 2019 - spandidos-publications.com
Anthracyclines are highly effective chemotherapeutic agents, used for a wide variety of
malignancies. Cardiotoxicity is a well‑recognized side effect of anthracycline therapy that …

[HTML][HTML] Acute kidney injury

JA Kellum, P Romagnani, G Ashuntantang… - Nature reviews Disease …, 2021 - nature.com
Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part
of a range of conditions summarized as acute kidney diseases and disorders (AKD), in …

Antioxidant therapy: current status and future prospects

O Firuzi, R Miri, M Tavakkoli… - Current medicinal …, 2011 - ingentaconnect.com
Reactive oxygen species (ROS) are widely believed to cause or aggravate several human
pathologies such as neurodegenerative diseases, cancer, stroke and many other ailments …

Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine

KQ De Andrade, FA Moura, JM Dos Santos… - International journal of …, 2015 - mdpi.com
Liver disease is highly prevalent in the world. Oxidative stress (OS) and inflammation are the
most important pathogenetic events in liver diseases, regardless the different etiology and …

Mitochondrial metabolism and targeted treatment strategies in ischemic-induced acute kidney injury

Y Chen, Z Li, H Zhang, H Chen, J Hao, H Liu… - Cell Death Discovery, 2024 - nature.com
Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The kidney
is susceptible to IRI under several clinical conditions, including hypotension, sepsis, and …

Clinical and pharmacological aspects of bath salt use: a review of the literature and case reports

K Miotto, J Striebel, AK Cho, C Wang - Drug and alcohol dependence, 2013 - Elsevier
Bath salts are designer drugs with stimulant properties that are a growing medical and
psychiatric concern due to their widespread availability and use. Although the chemical …