Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

The nomenclature and classification of vasculitis has been difficult and controversial for
many decades. This is problematic both for research on vasculitis as well as clinical care of …

Immunoglobin A (IgA) vasculitis (IgAV), formerly called the Henoch-Schönlein purpura
(HSP), is a small vessel vasculitis, characterized by IgA1-dominant immune deposition at …

Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …

IgA nephropathy is a common glomerular disease that is an important cause of kidney
failure. This review discusses advances in the therapy and understanding of the molecular …

Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …

The kidneys are frequently targeted by pathogenic immune responses against renal
autoantigens or by local manifestations of systemic autoimmunity. Recent studies in rodent …

Here we discuss recent advances in understanding the biochemical, immunologic, and
genetic pathogenesis of IgA nephropathy, the most common primary glomerulonephritis …

Importance The role of mycophenolate mofetil (MMF) in management of immunoglobulin A
nephropathy (IgAN) remains highly controversial. Objective To evaluate the efficacy and …

Complement activation has a role in the pathogenesis of IgA nephropathy, an autoimmune
disease mediated by pathogenic immune complexes consisting of galactose-deficient IgA1 …