Metabolic reprogramming in liver fibrosis
Chronic liver diseases, primarily metabolic dysfunction-associated steatotic liver disease
(MASLD), harmful use of alcohol, or viral hepatitis, may result in liver fibrosis, cirrhosis, and …
(MASLD), harmful use of alcohol, or viral hepatitis, may result in liver fibrosis, cirrhosis, and …
MASLD: A disease in flux
To coincide with the 20th anniversary of Nature Reviews Gastroenterology & Hepatology,
we asked three experts to reflect on the past, present and future of metabolic dysfunction …
we asked three experts to reflect on the past, present and future of metabolic dysfunction …
Deacetylation of HnRNP U mediated by sirtuin1 ameliorates aged rat with liver fibrosis via inhibiting p53-related senescence and NLRP3-related inflammation
J Liu, X Ma, W Guo, B Lu, Y Yue, X Yang… - International …, 2024 - Elsevier
Senescence represents a major risk factor promoting liver fibrosis progression. Sirtuin 1
(SIRT1), an essential regulator of cellular senescence, may be involved in developing liver …
(SIRT1), an essential regulator of cellular senescence, may be involved in developing liver …
Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies
X Di, Y Li, J Wei, T Li, B Liao - Advanced Science, 2024 - Wiley Online Library
As the final stage of disease‐related tissue injury and repair, fibrosis is characterized by
excessive accumulation of the extracellular matrix. Unrestricted accumulation of stromal …
excessive accumulation of the extracellular matrix. Unrestricted accumulation of stromal …
[HTML][HTML] Multi-Modal Analysis of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease
Background and aims Metabolic dysfunction-associated steatotic liver disease (MASLD)
ranges from Metabolic dysfunction-associated steatotic liver (MASL) to Metabolic …
ranges from Metabolic dysfunction-associated steatotic liver (MASL) to Metabolic …
Direct analysis of hepatic stellate cells with flow cytometry in specimens derived from the human liver
T Bando, H Morita, L Zreka, S Ma, M Khan, D Akuzawa… - 2024 - researchsquare.com
Background & Aims: Hepatic stellate cells (HSCs) play a crucial role in liver fibrosis.
However, the methodology to directly assess the biology of primary HSCs in human liver …
However, the methodology to directly assess the biology of primary HSCs in human liver …
[引用][C] Hepatic diseases at the molecular level: identifying novel targets and biomarkers through transcriptomics
C Sommerauer - 2024 - Inst för mikrobiologi, tumör-och …