Bacterial and host determinants of group B streptococcal infection of the neonate and infant

A Furuta, A Brokaw, G Manuel, M Dacanay… - Frontiers in …, 2022 - frontiersin.org
Group B streptococci (GBS) are Gram-positive β-hemolytic bacteria that can cause serious
and life-threatening infections in neonates manifesting as sepsis, pneumonia, meningitis …

Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine

T Canedo, CC Portugal, R Socodato… - …, 2021 - nature.com
Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational
purposes. Besides disrupting the monoaminergic system and promoting oxidative brain …

Meningeal regulation of infections: A double‐edged sword

E Eme‐Scolan, L Arnaud‐Paroutaud… - European Journal of …, 2023 - Wiley Online Library
In the past 10 years, important discoveries have been made in the field of neuroimmunology,
especially regarding brain borders. Indeed, meninges are protective envelopes surrounding …

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

V Mercado-Evans, ME Mejia, JJ Zulk, S Ottinger… - Nature …, 2024 - nature.com
Abstract Group B Streptococcus (GBS) is a pervasive perinatal pathogen, yet factors driving
GBS dissemination in utero are poorly defined. Gestational diabetes mellitus (GDM), a …

CC17 group B Streptococcus exploits integrins for neonatal meningitis development

RD de Cambronne, A Fouet, A Picart, AS Bourrel… - The Journal of clinical …, 2024 - jci.org
Group B Streptococcus (GBS) is the major cause of human neonatal infections. A single
clone, designated CC17-GBS, accounts for more than 80% of meningitis cases, the most …

[HTML][HTML] Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice

NM Gilbert, LR Foster, B Cao, Y Yin… - American journal of …, 2021 - Elsevier
Background Group B Streptococcus is a common vaginal bacterium and the leading cause
of invasive fetoplacental infections. Group B Streptococcus in the vagina can invade through …

Chlorogenic acid improves the cognitive deficits of sleep-deprived mice via regulation of immunity function and intestinal flora

H Zhu, F Shen, X Wang, H Qian, Y Liu - Phytomedicine, 2024 - Elsevier
Background Sleep deprivation (SD) has become a global health concern with serious
consequences containing memory deficits and gastrointestinal dysfunctions. The gut-brain …

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

CD Patel, IM Backes, SA Taylor, Y Jiang… - Science translational …, 2019 - science.org
Neonatal herpes simplex virus (nHSV) infections cause devastating morbidity and mortality
in infants. Most nHSV cases are associated with primary maternal infection, consistent with …

Human Milk Oligosaccharides Reduce Murine Group B Streptococcus Vaginal Colonization with Minimal Impact on the Vaginal Microbiota

ME Mejia, S Ottinger, A Vrbanac, P Babu, JJ Zulk… - Msphere, 2022 - Am Soc Microbiol
ABSTRACT Group B Streptococcus (GBS) colonizes the vaginal mucosa of a significant
percentage of healthy women and is a leading cause of neonatal bacterial infections …

Sex-specific maternofetal innate immune responses triggered by group B Streptococci

MJ Allard, A Giraud, M Segura, G Sebire - Scientific reports, 2019 - nature.com
Abstract Group B Streptococcus (GBS) is one of the most common bacteria isolated in
human chorioamnionitis, which is a major risk factor for premature birth and brain injuries …