Heart failure with preserved ejection fraction: JACC scientific statement
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …
Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets
BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …
intermingling epidemics driving perhaps the greatest unmet health problem in …
Heart failure with preserved ejection fraction: heterogeneous syndrome, diverse preclinical models
Heart failure with preserved ejection fraction (HFpEF) represents one of the greatest
challenges facing cardiovascular medicine today. Despite being the most common form of …
challenges facing cardiovascular medicine today. Despite being the most common form of …
The pathophysiology of heart failure with preserved ejection fraction
BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …
Inflammation in metabolic cardiomyopathy
Overlapping pandemics of lifestyle-related diseases pose a substantial threat to
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …
Cardiac metabolism in HFpEF: from fuel to signalling
Heart failure (HF) is marked by distinctive changes in myocardial uptake and utilization of
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
Pathophysiological basis of the cardiological benefits of SGLT-2 inhibitors: a narrative review
C Panico, B Bonora, A Camera, NC Chilelli… - Cardiovascular …, 2023 - Springer
In recent years, GLP-1 receptor agonists (GLP-1RA), and SGLT-2 inhibitors (SGLT-2i) have
become available, which have become valuable additions to therapy for type 2 diabetes as …
become available, which have become valuable additions to therapy for type 2 diabetes as …
Immunometabolic mechanisms of heart failure with preserved ejection fraction
GG Schiattarella, P Alcaide, G Condorelli… - Nature cardiovascular …, 2022 - nature.com
Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence worldwide,
already accounting for at least half of all cases of heart failure. As most patients with HFpEF …
already accounting for at least half of all cases of heart failure. As most patients with HFpEF …
[HTML][HTML] Glycolipid metabolic disorders, metainflammation, oxidative stress, and cardiovascular diseases: unraveling pathways
EP de Lima, RC Moretti Jr, K Torres Pomini… - Biology, 2024 - mdpi.com
Simple Summary Glycolipid metabolic disorders (GLMDs) result from imbalances in
glycolipid levels, leading to various health issues, including obesity, diabetes, liver …
glycolipid levels, leading to various health issues, including obesity, diabetes, liver …
Chronic low‐grade inflammation in heart failure with preserved ejection fraction
T Mesquita, YN Lin, A Ibrahim - Aging Cell, 2021 - Wiley Online Library
Heart failure (HF) with preserved ejection fraction (HFpEF) is currently the predominant form
of HF with a dramatic increase in risk with age. Low‐grade inflammation, as occurs with …
of HF with a dramatic increase in risk with age. Low‐grade inflammation, as occurs with …