Coffee by-products in topical formulations: A review

ÉM dos Santos, LM de Macedo, LL Tundisi… - Trends in Food Science …, 2021 - Elsevier
Background Coffee is of the most traded commodities in the world and its market has grown
regularly over the last 150 years. During production and processing of coffee beans many by …

Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy

S Mani, G Swargiary, SJ Ralph - Mitochondrion, 2022 - Elsevier
Abstract Changes in reactive oxygen species (ROS) levels affect many aspects of cell
behavior. During carcinogenesis, moderate ROS production modifies gene expression to …

[HTML][HTML] Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence-accelerated mouse prone 8 (SAMP8) …

S Aktar, F Ferdousi, S Kondo, T Kagawa, H Isoda - GeroScience, 2024 - Springer
In recent years, exploring natural compounds with functional properties to ameliorate aging-
associated cognitive decline has become a research priority to ensure healthy aging. In the …

[HTML][HTML] Trigonelline prevents kidney stone formation processes by inhibiting calcium oxalate crystallization, growth and crystal-cell adhesion, and downregulating …

P Peerapen, W Boonmark, V Thongboonkerd - Biomedicine & …, 2022 - Elsevier
Trigonelline is the second most abundant bioactive alkaloid found in coffee. It is classified as
a phytoestrogen with similar structure as of estradiol and exhibits an estrogenic effect. A …

Trigonelline induces browning in 3T3‐L1 white adipocytes

M Choi, S Mukherjee, JW Yun - Phytotherapy research, 2021 - Wiley Online Library
Trigonelline, a major alkaloid component of fenugreek, has been demonstrated to have
several biological activities, including antidiabetic and anticancer effects. This study aimed …

[HTML][HTML] Enzymatic synthesis of capric acid-rich structured lipids and their effects on mice with high-fat diet-induced obesity

JP Martínez-Galán, CM Ontibón-Echeverri… - Food Research …, 2021 - Elsevier
The objective of this study was to produce structured lipids (SLs) by enzymatic acidolysis
using Rhizopus oryzae lipase covalently immobilized in a low-cost material. Grape seed oil …

Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol

M Ashrafizadeh, S Javanmardi… - Bioscience …, 2020 - portlandpress.com
Mitochondria are intracellular organelles with two distinct membranes, known as an outer
mitochondrial membrane and inner cell membrane. Originally, mitochondria have been …

Prediction of a wide range of compounds concentration in raw coffee beans using NIRS, PLS and variable selection

JS Ribeiro, TJG Salva, MB Silvarolla - Food Control, 2021 - Elsevier
Near infrared spectroscopy coupled to chemometrics has been proposed as a low cost,
rapid and eco-friendly methodology in both off-line and on-line analyses of coffee beans and …

The pharmacological basis of the curcumin nutraceutical uses: An update

D Canistro, A Chiavaroli, D Cicia, F Cimino, D Curro… - Pharmadvances, 2021 - air.unimi.it
Curcumin is the major phytoconstituent found in the rhizomes of Curcuma longa L.
Preparations derived from the rhizome of the plant, referred as turmeric, have been used for …

The effects and molecular mechanism of heat stress on spermatogenesis and the mitigation measures

Y Gao, C Wang, K Wang, C He, K Hu… - Systems biology in …, 2022 - Taylor & Francis
Under normal conditions, to achieve optimal spermatogenesis, the temperature of the testes
should be 2–6° C lower than body temperature. Cryptorchidism is one of the common …