Objective To date, no systematic reviews and meta-analysis on the global epidemiology of
acromegaly are available in the literature. The aims of this study are to provide a systematic …

Transsphenoidal resection remains the standard treatment for most pituitary adenomas.
However, the ideal surgical approach to safely access these lesions, either microsurgical or …

Objective To study time‐related changes in the prevalence and patient characteristics of
acromegaly, as well as to assess the impact of changes in treatment on disease control …

Purpose Both prolactinomas and nonfunctioning adenomas (NFAs) can present with
hyperprolactinemia. Distinguishing them is critical because prolactinomas are effectively …

Purpose The pathogenesis of pituitary adenomas (PA) is complex. Ki-67, pituitary tumour
transforming gene (PTTG), vascular endothelial growth factor (VEGF), cyclin D1, c-MYC and …

Гормонально неактивные аденомы гипофиза представляют собой морфологически
гетерогенную группу и подразделяются на «немые» аденомы, которые обладают …

Abstract Context Acromegaly (ACM) and Cushing's disease (CD) are caused by functioning
pituitary adenomas secreting growth hormone and ACTH respectively. Objective To …

ABSTRACT Introduction Endocrine-disrupting chemicals (EDCs) have gained more
importance in the past decade, mostly due to their role in the pathogenesis of disease …

OBJECTIVE: Extracellular signal-regulated kinase (ERK)/mitogen activated protein kinase
(MAPK) signal pathway participates in cell proliferation, cycle, and apoptosis. MiR-16 is …

Purpose Patterns of extension of pituitary adenomas (PA) may vary according to PA subtype.
Understanding extrasellar extension patterns in growth hormone PAs (GHPA) vis-a-vis …