Plasmodium vivax: the potential obstacles it presents to malaria elimination and eradication

K Habtamu, B Petros, G Yan - Tropical Diseases, Travel Medicine and …, 2022 - Springer
Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …

African Plasmodium vivax malaria improbably rare or benign

JK Baird - Trends in Parasitology, 2022 - cell.com
The overwhelming dominance of Duffy blood group negativity among most people living in
sub-Saharan Africa has been considered the basis of their protection from endemic …

Prevalence and risk of Plasmodium vivax infection among Duffy-negative individuals: a systematic review and meta-analysis

P Wilairatana, FR Masangkay, KU Kotepui… - Scientific Reports, 2022 - nature.com
A better understanding of the occurrence and risk of Plasmodium vivax infection among
Duffy-negative individuals is required to guide further research on these infections across …

Genomic analysis of Plasmodium vivax describes patterns of connectivity and putative drivers of adaptation in Ethiopia

AM Kebede, E Sutanto, H Trimarsanto… - Scientific Reports, 2023 - nature.com
Ethiopia has the greatest burden of Plasmodium vivax in Africa, but little is known about the
epidemiological landscape of parasites across the country. We analysed the genomic …

Complement receptor 1 is the human erythrocyte receptor for Plasmodium vivax erythrocyte binding protein

SK Lee, C Crosnier… - Proceedings of the …, 2024 - National Acad Sciences
The discovery that Africans were resistant to infection by Plasmodium vivax (P. vivax) led to
the conclusion that P. vivax invasion relied on the P. vivax Duffy Binding Protein (PvDBP) …

Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia

A Abate, I Bouyssou, S Mabilotte, C Doderer-Lang… - Malaria Journal, 2022 - Springer
Background The increase in detections of Plasmodium vivax infection in Duffy-negative
individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy …

The Black Box of Cellular and Molecular Events of Plasmodium vivax Merozoite Invasion into Reticulocytes

J Molina-Franky, C Reyes, YA Picón Jaimes… - International Journal of …, 2022 - mdpi.com
Plasmodium vivax is the most widely distributed malaria parasite affecting humans
worldwide, causing~ 5 million cases yearly. Despite the disease's extensive burden, there …

[HTML][HTML] Plasmodium vivax in sub-Saharan Africa: an advancing threat to malaria elimination?

MA Oboh-Imafidon, PA Zimmerman - The American Journal of …, 2023 - ncbi.nlm.nih.gov
P. malariae and P. ovale with and without P. falciparum, 4-8 cases of P. vivax have been
thought to be absent in sSA due to the erythrocyte silent Duffy-negative phenotype across a …

Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence

A Abebe, I Bouyssou, S Mabilotte… - PLoS neglected …, 2023 - journals.plos.org
Background The interaction between the Plasmodium vivax Duffy-binding protein and the
corresponding Duffy Antigen Receptor for Chemokines (DARC) is primarily responsible for …

Relationship between Duffy Genotype/Phenotype and Prevalence of Plasmodium vivax Infection: A Systematic Review

YA Picon-Jaimes, ID Lozada-Martinez… - Tropical Medicine and …, 2023 - mdpi.com
The Duffy protein, a transmembrane molecule, functions as a receptor for various
chemokines and facilitates attachment between the reticulocyte and the Plasmodium Duffy …