The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Noncoding RNAs in gastric cancer: implications for drug resistance

L Wei, J Sun, N Zhang, Y Zheng, X Wang, L Lv, J Liu… - Molecular cancer, 2020 - Springer
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-
related deaths worldwide. Advanced gastric cancer patients can notably benefit from …

Tumor immune microenvironment lncRNAs

EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of …

L Zhou, J Jiang, Z Huang, P Jin, L Peng, M Luo… - Molecular cancer, 2022 - Springer
Background Hypoxia, a typical hallmark of solid tumors, exhibits an essential role in the
progression of colorectal cancer (CRC), in which the dysregulation of long non-coding RNAs …

Long non-coding RNA: Classification, biogenesis and functions in blood cells

S Dahariya, I Paddibhatla, S Kumar… - Molecular …, 2019 - Elsevier
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation

Y Luo, S Zheng, Q Wu, J Wu, R Zhou, C Wang, Z Wu… - Autophagy, 2021 - Taylor & Francis
Chemotherapy is currently the main treatment for unresectable or advanced postoperative
gastric cancers. However, its efficacy is negatively affected by the occurrence of …

ceRNA in cancer: possible functions and clinical implications

X Qi, DH Zhang, N Wu, JH Xiao, X Wang… - Journal of medical …, 2015 - jmg.bmj.com
Competing endogenous RNAs (ceRNAs) are transcripts that can regulate each other at post-
transcription level by competing for shared miRNAs. CeRNA networks link the function of …

Long non-coding RNAs and complex diseases: from experimental results to computational models

X Chen, CC Yan, X Zhang, ZH You - Briefings in bioinformatics, 2017 - academic.oup.com
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

LncRNA HOXA11-AS promotes proliferation and invasion of gastric cancer by scaffolding the chromatin modification factors PRC2, LSD1, and DNMT1

M Sun, F Nie, Y Wang, Z Zhang, J Hou, D He, M Xie… - Cancer research, 2016 - AACR
Long noncoding RNAs (lncRNA) have been implicated in human cancer but their
mechanisms of action are mainly undocumented. In this study, we investigated lncRNA …