A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

M Barnett, D Wang, H Beadnall, A Bischof… - npj Digital …, 2023 - nature.com
Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical
relapses, no magnetic resonance imaging (MRI) disease activity and no disability …

Consensus Guidelines of the French Society of Neuroradiology (SFNR) on the use of Gadolinium-Based Contrast agents (GBCAs) and related MRI protocols in …

F Lersy, G Boulouis, O Clément, H Desal… - Journal of …, 2020 - Elsevier
Gadolinium-based contrast agents (GBCAs) are used in up to 35% of magnetic resonance
imaging (MRI) examinations and are associated with an excellent safety profile …

[HTML][HTML] Multiple sclerosis lesions segmentation from multiple experts: The MICCAI 2016 challenge dataset

O Commowick, M Kain, R Casey, R Ameli, JC Ferré… - Neuroimage, 2021 - Elsevier
MRI plays a crucial role in multiple sclerosis diagnostic and patient follow-up. In particular,
the delineation of T2-FLAIR hyperintense lesions is crucial although mostly performed …

MRI and laboratory monitoring of disease-modifying therapy efficacy and risks

M Barnett, Y Barnett, S Reddel - Current Opinion in Neurology, 2022 - journals.lww.com
A biomarker-enhanced monitoring strategy has immediate clinical application, with growing
evidence of long-term reductions in disability accrual when both clinically symptomatic and …

Prognostic accuracy of NEDA-3 in long-term outcomes of multiple sclerosis

L Prosperini, S Ruggieri, S Haggiag… - Neurology …, 2021 - AAN Enterprises
Background and Objectives To estimate the proportions of patients with relapsing-remitting
multiple sclerosis who despite achieving the no evidence of disease activity-3 (NEDA-3) …

Automatic segmentation of white matter hyperintensities: validation and comparison with state-of-the-art methods on both Multiple Sclerosis and elderly subjects

P Tran, U Thoprakarn, E Gourieux, CL Dos Santos… - NeuroImage: Clinical, 2022 - Elsevier
Different types of white matter hyperintensities (WMH) can be observed through MRI in the
brain and spinal cord, especially Multiple Sclerosis (MS) lesions for patients suffering from …

Deeply 3D-T1-TFE hypointense voxels are characteristic of phase-rim lesions in multiple sclerosis

P Naval-Baudin, A Pons-Escoda, À Camins… - European …, 2024 - Springer
Objectives The development of new drugs for the treatment of progressive multiple sclerosis
(MS) highlights the need for new prognostic biomarkers. Phase-rim lesions (PRLs) have …

[HTML][HTML] Automatic methods for multiple sclerosis new lesions detection and segmentation

O Commowick, B Combès, F Cervenansky… - Frontiers in …, 2023 - frontiersin.org
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting more than half a million persons in Europe, with a prevalence rate of 83 per …

[HTML][HTML] A clinically-compatible workflow for computer-aided assessment of brain disease activity in multiple sclerosis patients

B Combès, A Kerbrat, G Pasquier… - Frontiers in …, 2021 - frontiersin.org
Over the last 10 years, the number of approved disease modifying drugs acting on the focal
inflammatory process in Multiple Sclerosis (MS) has increased from 3 to 10. This wide …

Alternatives to gadolinium-based contrast agents

MF Tweedle - Investigative Radiology, 2021 - journals.lww.com
Gadolinium-based contrast agents have been used in hundreds of millions of patients in the
past 30 years, with an exemplary safety record. However, assumptions made at their …