Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …
chemotherapeutic drugs have shown considerable potential to reverse the …
Recent progress in nanotechnology-based drug carriers for resveratrol delivery
C Li, Z Wang, H Lei, D Zhang - Drug delivery, 2023 - Taylor & Francis
Resveratrol is a polyphenol with diverse pharmacological activities, but its clinical efficacy is
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity
The effective chemotherapeutic drug, doxorubicin (DOX), elicits immunogenic cell death
(ICD) and additional anticancer immune responses during chemotherapy. However, it also …
(ICD) and additional anticancer immune responses during chemotherapy. However, it also …
Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy
W Xia, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …
receive chemotherapy and radiotherapy, but these treatments are usually only partially …
Emerging albumin-binding anticancer drugs for tumor-targeted drug delivery: current understandings and clinical translation
Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …
Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges
Obesity affects more than 650 million individuals worldwide and is a well-established risk
factor for the development of hepatocellular carcinoma (HCC). Oxidative stress can be …
factor for the development of hepatocellular carcinoma (HCC). Oxidative stress can be …
Therapeutic silencing of BCL-2 using NK cell-derived exosomes as a novel therapeutic approach in breast cancer
K Kaban, C Hinterleitner, Y Zhou, E Salva, AG Kantarci… - Cancers, 2021 - mdpi.com
Simple Summary Overexpression of the antiapoptotic protein BCL-2 is correlated with
estrogen receptor (ER) expression in breast cancer and plays an important role for disease …
estrogen receptor (ER) expression in breast cancer and plays an important role for disease …
PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery
Combination therapies involving anticancer drugs and gene therapy agents have become a
potential treatment for different cancer types reducing the side effects of anticancer drugs …
potential treatment for different cancer types reducing the side effects of anticancer drugs …
The safe and effective intraperitoneal chemotherapy with cathepsin B-specific doxorubicin prodrug nanoparticles in ovarian cancer with peritoneal carcinomatosis
Intraperitoneal (IP) chemotherapy has shown promising efficacy in ovarian cancer with
peritoneal carcinomatosis (PC), but in vivo rapid clearance and severe toxicity of free …
peritoneal carcinomatosis (PC), but in vivo rapid clearance and severe toxicity of free …
How did conventional nanoparticle-mediated photothermal therapy become “hot” in combination with cancer immunotherapy?
Simple Summary Photothermal therapy (PTT) has become effective through the
development of nanoparticle-based photoabsorbers with various functions, such as …
development of nanoparticle-based photoabsorbers with various functions, such as …