Moderate‐Intensity Exercise Maintains Redox Homeostasis for Cardiovascular Health

J Jiang, L Ni, X Zhang, P Gokulnath… - Advanced …, 2023 - Wiley Online Library
It is well known that exercise is beneficial for cardiovascular health. Oxidative stress is the
common pathological basis of many cardiovascular diseases. The overproduction of free …

Central and peripheral chemoreflexes in humans with treated hypertension

ALC Sayegh, JL Fan, M Dawes… - The Journal of …, 2023 - Wiley Online Library
Increased peripheral chemoreflex sensitivity is a pathogenic feature of human hypertension
(HTN), while both central and peripheral chemoreflex sensitivities are reportedly augmented …

Potential role of the retrotrapezoid nucleus in mediating cardio-respiratory dysfunction in heart failure with preserved ejection fraction

C Toledo, D Ortolani, FC Ortiz, NJ Marcus… - Frontiers in …, 2022 - frontiersin.org
A strong association between chemoreflex hypersensitivity, disordered breathing, and
elevated sympathetic activity has been shown in experimental and human heart failure (HF) …

[HTML][HTML] Superoxide dismutase 2 deficiency is associated with enhanced central chemoreception in mice: Implications for breathing regulation

E Díaz-Jara, K Pereyra, S Vicencio, MA Olesen… - Redox Biology, 2024 - Elsevier
Aims In mammals, central chemoreception plays a crucial role in the regulation of breathing
function in both health and disease conditions. Recently, a correlation between high levels …

[HTML][HTML] The effect of progressive endurance training and extract of black winter truffle on proteins levels and expression of hippocampus α-synuclein and HSF1 in the …

ME Peer, Z Fallahmohammadi, A Akbari - Metabolism Open, 2023 - Elsevier
Aim The research aimed to investigate the effect of endurance running and T. Brumale
extract on α-Syn and HSF1 in the brain and serum of healthy and diabetic rats. Methods A …

Lipid-Encapsuled Grape Tannins Prevent Oxidative-Stress-Induced Neuronal Cell Death, Intracellular ROS Accumulation and Inflammation

HS Díaz, A Ríos-Gallardo, D Ortolani, E Díaz-Jara… - Antioxidants, 2022 - mdpi.com
The central nervous system (CNS) is particularly vulnerable to oxidative stress and
inflammation, which affect neuronal function and survival. Nowadays, there is great interest …

Sleep dysregulation in sympathetic-mediated diseases: implications for disease progression

MJ Olivares, C Toledo, D Ortolani, FC Ortiz, HS Díaz… - Sleep, 2022 - academic.oup.com
The autonomic nervous system (ANS) plays an important role in the coordination of several
physiological functions including sleep/wake process. Significant changes in ANS activity …

Muscle FOXO-specific overexpression and endurance exercise protects skeletal muscle and heart from defects caused by a high-fat diet in young Drosophila

D Wen, Y Chen, W Hou - bioRxiv, 2022 - biorxiv.org
Obesity appears to significantly reduce physical activity, but it remains unclear whether this
is related to obesity-induced damage to skeletal muscle (SM) and heart muscle (HM) …

miR-21 Overexpression Ameliorates the Myocardial Injury and Inflammation and Oxidative Stress

C Lu, G Jiang, X Zhao - Journal of Biomaterials and Tissue …, 2022 - ingentaconnect.com
This study assessed the effect of miR-21 overexpression on the myocardial injury and
inflammation and oxidative stress. Bone marrow mesenchymal stem cells (BMSCs) of rats …

miR-663-Containing Exosomes Secreted by Bone Marrow Mesenchymal Stem Cells Ameliorate Cardiomyocyte Oxidative Damage

X Xia, B Xu - Journal of Biomaterials and Tissue Engineering, 2023 - ingentaconnect.com
This study assesses the role of miR-663 in the oxidative damage in myocardial cells through
regulating BMSC from exosome. BMSC from rats was cultivated and transfected with miR …