Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
[HTML][HTML] The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis
FJI Fowkes, JS Richards, JA Simpson… - PLoS medicine, 2010 - journals.plos.org
Background One of the criteria to objectively prioritize merozoite antigens for malaria
vaccine development is the demonstration that naturally acquired antibodies are associated …
vaccine development is the demonstration that naturally acquired antibodies are associated …
[HTML][HTML] Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte
Erythrocyte invasion by the merozoite is an obligatory stage in Plasmodium parasite
infection and essential to malaria disease progression. Attempts to study this process have …
infection and essential to malaria disease progression. Attempts to study this process have …
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
During blood-stage infection by Plasmodium falciparum, merozoites invade RBCs. Currently
there is limited knowledge of cellular and molecular invasion events, and no established …
there is limited knowledge of cellular and molecular invasion events, and no established …
[HTML][HTML] Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker …
JS Richards, TU Arumugam, L Reiling… - The Journal of …, 2013 - journals.aai.org
The development of effective malaria vaccines and immune biomarkers of malaria is a high
priority for malaria control and elimination. Ags expressed by merozoites of Plasmodium …
priority for malaria control and elimination. Ags expressed by merozoites of Plasmodium …
[HTML][HTML] Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity
Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
[HTML][HTML] Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
[HTML][HTML] Malaria eradication and elimination: views on how to translate a vision into reality
Although global efforts in the past decade have halved the number of deaths due to malaria,
there are still an estimated 219 million cases of malaria a year, causing more than half a …
there are still an estimated 219 million cases of malaria a year, causing more than half a …
Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and …
DI Stanisic, FJI Fowkes, M Koinari, S Javati… - Infection and …, 2015 - Am Soc Microbiol
Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after
repeated exposure. Knowledge of the acquisition and nature of protective immune …
repeated exposure. Knowledge of the acquisition and nature of protective immune …
Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density …
JS Richards, DI Stanisic, FJI Fowkes… - Clinical Infectious …, 2010 - academic.oup.com
Background. Antibodies targeting blood stage antigens are important in protection against
malaria, but the principle targets remain unclear. Erythrocyte-binding antigens (EBAs) are …
malaria, but the principle targets remain unclear. Erythrocyte-binding antigens (EBAs) are …