Context Although the widespread use of prostate-specific antigen (PSA) has led to an early
detection of prostate cancer (PCa) and a reduction of metastatic disease at diagnosis, PSA …

Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …

Following detection of high levels of serum prostate-specific antigen, many men are advised
to have transrectal ultrasound-guided biopsy in an attempt to locate a cancer. This …

BACKGROUND: The diagnosis of prostate cancer (PCa) is currently based on serum PSA
testing and/or abnormal digital rectal examination and histopathologic evaluation of prostate …

Simple Summary In prostate cancer, overdiagnosis and overtreatment is a common problem
for clinicians. Accurate diagnosis and prognosis are essential to avoid unnecessary biopsy …

Although prostate cancer (PCa) is the most commonly diagnosed cancer in men, most
patients do not die from the disease. Prostate specific antigen (PSA), the most widely used …

Metabolite profiling is being increasing employed in the study of prostate cancer as a means
of identifying predictive, diagnostic, and prognostic biomarkers. This review provides a …

Results Limited specificity of the prostate-specific antigen (PSA) test brings a need to
develop new and better diagnostic tools. In the last few years, new approaches for providing …

Simple Summary The lack of highly specific and sensitive biomarkers for the early detection
of prostate cancer (PCa) is a major barrier to its management. Volatilomics emerged as a …

Both multi-parametric MRI (mpMRI) and the Prostate Health Index (PHI) have shown
promise in predicting a positive biopsy in men with suspected prostate cancer. Here we …