Pre-metastatic niche: formation, characteristics and therapeutic implication

Y Wang, J Jia, F Wang, Y Fang, Y Yang… - … and Targeted Therapy, 2024 - nature.com
Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Role of Extracellular Vesicles in the Progression of Brain Tumors

G Schiera, CM Di Liegro, F Vento, I Di Liegro - Biology, 2024 - pmc.ncbi.nlm.nih.gov
Brain tumors, and, in particular, glioblastoma (GBM), are among the most aggressive forms
of cancer. In spite of the advancement in the available therapies, both diagnosis and …

Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing

N van Bree, AS Oppelt, S Lindström, L Zhou… - Neuro …, 2024 - academic.oup.com
Background Medulloblastoma (MB) is one of the most common malignant brain tumors in
children. Current preclinical in vivo model systems for MB have increased our understanding …

Nanoparticles for efficient drug delivery and drug resistance in glioma: New perspectives

J Liu, F Yang, J Hu, X Zhang - CNS Neuroscience & …, 2024 - Wiley Online Library
Gliomas are the most common primary tumors of the central nervous system, with
glioblastoma multiforme (GBM) having the highest incidence, and their therapeutic efficacy …

Clinical and Genomic Phenotype of Brain Metastasis in Nasopharyngeal Carcinoma

Y Peng, S Yang, J He, Q Liu, X Li, F Kong… - Molecular …, 2024 - Wiley Online Library
Brain metastasis in nasopharyngeal carcinoma is a rare but poor prognosis clinical problem.
This study aims to investigate the clinical characteristics and identify the genomic profiling of …

[HTML][HTML] The molecular and immune microenvironmental landscape of brain metastases: Implications for novel treatment options

S Li, Y Shen, C Dong, S Yin, D Zhou, A Zhou - Cell Investigation, 2025 - Elsevier
Brain metastases (BM), in which cells from a primary malignant tumor spread through the
circulatory system into the microvasculature of the brain, eventually progress despite …