Mouse models of sepsis and septic shock

KV Korneev - Molecular Biology, 2019 - Springer
An extensive network of regulation of systemic inflammation makes development of a
reproducible experimental model of sepsis a complex task. There is no single mouse model …

The current evidence for the treatment of sepsis with Xuebijing injection: Bioactive constituents, findings of clinical studies and potential mechanisms

C Li, P Wang, M Li, R Zheng, S Chen, S Liu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Xuebijing (XBJ) injection is a Chinese medicine
containing extracts from Carthamus tinctorius L.(Carthami Flos, hong hua, Asteraceae) …

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes

G Di Venanzio, AL Flores-Mireles, JJ Calix… - Nature …, 2019 - nature.com
Multidrug resistant (MDR) Acinetobacter baumannii poses a growing threat to global health.
Research on Acinetobacter pathogenesis has primarily focused on pneumonia and …

Host Innate Immune Responses to Acinetobacter baumannii Infection

W Chen - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
Acinetobacter baumannii has emerged as a major threat to global public health and is one
of the key human pathogens in healthcare (nosocomial and community-acquired) …

Anti-outer Membrane Vesicle Antibodies Increase Antibiotic Sensitivity of Pan-Drug-Resistant Acinetobacter baumannii

W Huang, Q Zhang, W Li, Y Chen, C Shu, Q Li… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii often causes serious nosocomial infections. Because of its serious
drug resistance problems, complex drug resistance mechanism, and rapid adaptation to …

IL-10 Protects Mice From the Lung Infection of Acinetobacter baumannii and Contributes to Bacterial Clearance by Regulating STAT3-Mediated MARCO Expression …

MJ Kang, AR Jang, JY Park, JH Ahn, TS Lee… - Frontiers in …, 2020 - frontiersin.org
Interleukin-10 plays important, yet contrasting, roles in host protection against bacterial
infections and in the septic response. To determine the role of IL-10 in the host defense …

Insights into Acinetobacter baumannii protective immunity

S Jeffreys, JP Chambers, JJ Yu, CY Hung… - Frontiers in …, 2022 - frontiersin.org
Acinetobacter baumannii is a nosocomic opportunistic Gram-negative bacteria known for its
extensive drug-resistant phenotype. A. baumannii hospital-acquired infections are major …

Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice

R López-Díez, X Shen, G Daffu… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Diabetic subjects are at higher risk of ischemic peripheral vascular disease. We
tested the hypothesis that advanced glycation end products (AGEs) and their receptor …

Endogenous uteroglobin as intrinsic anti-inflammatory signal modulates monocyte and macrophage subsets distribution upon sepsis induced lung injury

A Janicova, N Becker, B Xu, S Wutzler… - Frontiers in …, 2019 - frontiersin.org
Sepsis is a serious clinical condition which can cause life-threatening organ dysfunction,
and has limited therapeutic options. The paradigm of limiting excessive inflammation and …

Expanding the current knowledge about the role of interleukin-10 to major concerning bacteria

HF Peñaloza, LP Noguera, CA Riedel… - Frontiers in …, 2018 - frontiersin.org
Interleukin-10 (IL-10) is one of the most important anti-inflammatory cytokine produced
during bacterial infection. Two related phenomena explain the importance of IL-10 …