[HTML][HTML] Fibrous matrices facilitate pleurocidin killing of wound associated bacterial pathogens

C Ramos, K Lorenz, M Putrinš, CK Hind, A Meos… - European Journal of …, 2024 - Elsevier
Conventional wound infection treatments neither actively promote wound healing nor
address the growing problem of antibacterial resistance. Antimicrobial peptides (AMPs) are …

Effect of central PxxP motif in amphipathic alpha-helical peptides on antimicrobial activity and mode of action

H Lee, S Yang, SH Shin - Journal of Analytical Science and Technology, 2023 - Springer
Amphipathic α-helical peptides (AHPs) have shown potential as a therapeutic approach
against multi-drug-resistant bacterial infections due to their broad-spectrum antimicrobial …

Rifampin- or Capreomycin-Induced Remodeling of the Mycobacterium smegmatis Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic …

DDKW Man, T Kanno, G Manzo, BD Robertson… - Msphere, 2018 - Am Soc Microbiol
The mycobacterial cell wall affords natural resistance to antibiotics. Antimicrobial peptides
(AMPs) modify the surface properties of mycobacteria and can act synergistically with …

Molecular Dynamics Study of the Human Beta-defensins 2 and 3 Chimeric Peptides with the Cell Membrane Model of Pseudomonas aeruginosa

MD Ghafari, I Rasooli, K Khajeh… - International Journal of …, 2020 - Springer
Pseudomonas aeruginosa is a unique microorganism among the antibiotic-resistant
microbial pathogens. Among the various therapeutic approaches, antimicrobial peptides are …

optimizing exogenous Surfactant as a pulmonary Delivery Vehicle for Chicken Cathelicidin-2

B Baer, EJA Veldhuizen, N Molchanova… - Scientific Reports, 2020 - nature.com
The rising incidence of antibiotic-resistant lung infections has instigated a much-needed
search for new therapeutic strategies. One proposed strategy is the use of exogenous …

Characterization of Antimicrobial Peptide–Membrane Interaction Using All-Atom Molecular Dynamic Simulation

S Mukherjee, RK Kar, A Bhunia - Immunity in Insects, 2020 - Springer
The investigation of peptides interaction with cell membranes is essential for understanding
the basic functions such as membrane transport, fusion, and signaling processes, which …

Rifampicin or capreomycin induced remodelling of the Mycobacterium smegmatis mycolic acid layer is mitigated in synergistic combinations with cationic …

DDKW Man, T Kanno, G Manzo, BD Robertson… - bioRxiv, 2018 - biorxiv.org
The mycobacterial cell wall affords natural resistance to antibiotics. Antimicrobial peptides
(AMPs) modify the surface properties of mycobacteria and can act synergistically with …