Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Production of scandium radionuclides for theranostic applications: towards standardization of quality requirements

R Mikolajczak, S Huclier-Markai, C Alliot… - EJNMMI …, 2021 - Springer
In the frame of “precision medicine”, the scandium radionuclides have recently received
considerable interest, providing personalised adjustment of radiation characteristics to …

De novo approaches to the solid-phase separation of Titanium (IV) and Scandium (III): translating speciation data to selective on-bead chelation toward applications in …

AJ Koller, L Wang, M Deluca, O Glaser… - Inorganic …, 2023 - ACS Publications
The solution chemistry of the hydrolytic, early-transition-metal ions Ti4+ and Sc3+ represents
a coordination chemistry challenge with important real-world implications, specifically in the …

Radiochemistry with {Al18F} 2+: Current status and optimization perspectives for efficient radiofluorination by complexation

S Schmitt, E Moreau - Coordination Chemistry Reviews, 2023 - Elsevier
With the aim to efficiently develop and synthesize new radiotracers for PET imaging, and
their use for theranostic approaches, radiolabeling technics have not ceased to progress …

Emerging chelators for nuclear imaging

D Sneddon, B Cornelissen - Current Opinion in Chemical Biology, 2021 - Elsevier
Chelators are necessary in nuclear medicine imaging to direct an inorganic radionuclide, a
radiometal, to a desired target; unfortunately, there is no 'one-size-fits-all'chelator. As the …

d0 Metal-Catalyzed Alkyl–Alkyl Cross-Coupling Enabled by a Redox-Active Ligand

RG Belli, VC Tafuri, MV Joannou, CC Roberts - ACS Catalysis, 2022 - ACS Publications
Alkyl–alkyl cross-coupling through well-defined mechanisms that allow for controlled
oxidative addition, prevent β-hydride elimination, and tolerate hindered electrophiles is still …

Sc-HOPO: a potential construct for use in radioscandium-based radiopharmaceuticals

MD Phipps, S Cingoranelli… - Inorganic …, 2023 - ACS Publications
Three isotopes of scandium─ 43Sc, 44Sc, and 47Sc─ have attracted increasing attention
as potential candidates for use in imaging and therapy, respectively, as well as for possible …

Scandium–microorganism interactions in new biotechnologies

V Syrvatka, A Rabets, O Gromyko, A Luzhetskyy… - Trends in …, 2022 - cell.com
Scandium (Sc) plays a special role in high-tech industries because of its wide application in
green, space, and defense technologies. However, Sc mining and purification are …

Sacrificial-Hydroxamate-Enabled Sizable Crystallization of Scandium Carboxylate Metal–Organic Frameworks

W Wu, W Tang, ZW Shao, X Feng, L Xiong… - Inorganic …, 2024 - ACS Publications
Starting from labile hydroxamic acid ligands that are strong chelators, here, we implemented
a sacrificial modulating strategy to prepare a series of scandium carboxylate metal–organic …

Exploring Aqueous Coordination Chemistry of Highly Lewis Acidic Metals with Emerging Isotopes for Nuclear Medicine

JN Whetter, D Śmiłowicz, E Boros - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Nuclear medicine harnesses radioisotopes for the diagnosis and treatment of
disease. While the isotopes 99mTc and 111In have enabled the clinical diagnosis of millions …