Pyridine compounds with antimicrobial and antiviral activities
M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
Development of novel indolin-2-one derivative incorporating thiazole moiety as DHFR and quorum sensing inhibitors: Synthesis, antimicrobial, and antibiofilm …
AY Alzahrani, YA Ammar, M Abu-Elghait, MA Salem… - Bioorganic …, 2022 - Elsevier
Nowadays, it's imperative to develop novel antimicrobial agents active against both drug-
sensitive and drug-resistant bacterial infections with favorable profiles as high efficacy, low …
sensitive and drug-resistant bacterial infections with favorable profiles as high efficacy, low …
Synthesis, characterization, thermal properties, antimicrobial evaluation, ADMET study, and molecular docking simulation of new mono Cu (II) and Zn (II) complexes …
One of the interesting research fields is developing and assessing novel metal-containing
medications. A new isatin-3-thiosemicarbazone derivative 4 was synthesized by two …
medications. A new isatin-3-thiosemicarbazone derivative 4 was synthesized by two …
Synthesis, characterization, and in vitro antibacterial activity of some new pyridinone and pyrazole derivatives with some in silico ADME and molecular modeling study
KE Saadon, NMH Taha, NA Mahmoud… - Journal of the Iranian …, 2022 - Springer
A new series of pyridine-2-one and pyrazole derivatives were designed and synthesized
based on cyanoacrylamide derivatives containing 2, 4-dichlro aniline and 6-methyl 2-amino …
based on cyanoacrylamide derivatives containing 2, 4-dichlro aniline and 6-methyl 2-amino …
Evaluation of the anti-proliferative activity of 2-oxo-pyridine and 1′ H-spiro-pyridine derivatives as a new class of EGFR Wt and VEGFR-2 inhibitors with apoptotic …
RR Raslan, YA Ammar, SA Fouad, SA Hessein… - RSC …, 2023 - pubs.rsc.org
Developing new agents for cancer treatment remains a top priority because it is one of the
deadliest worldwide. A new series of 2-oxo-pyridine and 1′ H-spiro-pyridine derivatives …
deadliest worldwide. A new series of 2-oxo-pyridine and 1′ H-spiro-pyridine derivatives …
Coordination compounds of pyrazolone‐based ligand: Design, characterization, biological evaluation, antitumor efficiency, and DNA binding evaluation supported by …
SA Ibrahim, A Ragab… - Applied Organometallic …, 2022 - Wiley Online Library
Abstract Cu (II), Ni (II), Mn (II), and Cr (III) chelates of the organic ligand named 3‐(furan‐2‐
yl)‐5‐oxo‐N, 1‐diphenyl‐4, 5‐dihydro‐1H‐pyrazole‐4‐carbothioamide ligand (abbreviated …
yl)‐5‐oxo‐N, 1‐diphenyl‐4, 5‐dihydro‐1H‐pyrazole‐4‐carbothioamide ligand (abbreviated …
Synthesis, spectral characterization, antimicrobial evaluation and molecular docking studies of new Cu (II), Zn (II) thiosemicarbazone based on sulfonyl isatin
Abstract Reaction of 5-(morpholinisulfonyl) isatin (1) with thiosemicarbazide derivative
appended the corresponding thiosemicarbazone derivative 3 that further coordinated with …
appended the corresponding thiosemicarbazone derivative 3 that further coordinated with …
[HTML][HTML] In vitro antimicrobial evaluation, single-point resistance study, and radiosterilization of novel pyrazole incorporating thiazol-4-one/thiophene derivatives as …
HA Mohamed, YA Ammar, GAM Elhagali, HA Eyada… - ACS …, 2022 - ncbi.nlm.nih.gov
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination …
Microbial resistance is a big concern worldwide, making the development of new
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …
[HTML][HTML] Design, synthesis of new novel quinoxalin-2 (1H)-one derivatives incorporating hydrazone, hydrazine, and pyrazole moieties as antimicrobial potential with in …
Abstract A series of 6-(morpholinosulfonyl) quinoxalin-2 (1H)-one based hydrazone,
hydrazine, and pyrazole moieties were designed, synthesized, and evaluated for their in …
hydrazine, and pyrazole moieties were designed, synthesized, and evaluated for their in …