Roles of ferroptosis in urologic malignancies

S Zhao, P Li, W Wu, Q Wang, B Qian, X Li… - Cancer cell …, 2021 - Springer
Ferroptosis, an iron-dependent form of non-apoptotic cell death, is believed to strongly
contribute to the pathogenesis of multiple cancers. Recently, the positive association …

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) …

X Zheng, Q Wang, Y Zhou, D Zhang… - Cancer …, 2022 - Wiley Online Library
Abstract Background N‐acetyltransferase 10 (NAT10) is the only enzyme known to mediate
the N4‐acetylcytidine (ac4C) modification of mRNA and is crucial for mRNA stability and …

The mechanistic role of NAT10 in cancer: unraveling the enigmatic web of oncogenic signaling

P Rodrigues, H Bangali, E Ali… - … -Research and Practice, 2023 - Elsevier
Abstract N-acetyltransferase 10 (NAT10), a versatile enzyme, has gained considerable
attention as a significant player in the complex realm of cancer biology. Its enigmatic role in …

A novel protein encoded by circFOXP1 enhances ferroptosis and inhibits tumor recurrence in intrahepatic cholangiocarcinoma

P Wang, Z Hu, S Yu, S Su, R Wu, C Chen, Y Ye… - Cancer Letters, 2024 - Elsevier
CircRNAs participates in the development and occurrence of multiple tumor types. However,
the specific effects and underlying mechanisms of circRNA in intrahepatic …

肾癌铁死亡相关研究进展

谢仕萍, 王玉杰 - 临床泌尿外科杂志, 2024 - whuhzzs.com
从细胞凋亡到坏死性凋亡到焦亡, 再发展到现在的铁死亡和铜死亡. 细胞死亡相关研究在肿瘤中
的作用至关重要, 铁死亡作为一种铁离子依赖性的程序性细胞死亡, 其特征包括脂质过氧化物 …

SETD2 deficiency promotes the transition from PKD to ccRCC by dysregulation of sphingomyelin metabolism

Y Zhang, C Liu, T Ye, L Chen, X Yang, L Zhou, H An - bioRxiv, 2022 - biorxiv.org
Clear cell renal cell carcinoma (ccRCC) is a malignant tumor with dysregulated lipid
metabolism, and is highly incidental in polycystic kidney disease (PKD) patients. However …