Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

Microfluidics opened the possibility to model the physiological environment by controlling
fluids flows, and therefore nutrients supply. It allows to integrate external stimuli such as …

Immunocyte infiltration and cytotoxicity play critical roles in both inflammation and
immunotherapy. However, current cancer immunotherapy screening methods overlook the …

The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

Understanding of human brain development, dysfunction and neurological diseases has
remained limited and challenging due to inability to recapitulate human brain-specific …

The discovery of new pain therapeutics targeting human nociceptive circuitry is an
emerging, exciting, and rewarding field. However, current models for evaluating prospective …

Acoustofluidic technologies that integrate acoustic waves and microfluidic chips have been
widely used in bioparticle manipulation. As a representative technology, acoustic tweezers …

Cancer models, which are biologically representative of patient tumors, can predict the
treatment responses and help determine the most appropriate cancer treatment for …

Transitioning our society to a sustainable future, with low or net-zero carbon emissions to the
atmosphere, will require a wide-spread transformation of energy and environmental …

Abstract pioids are commonly used for treating chronic pain. However, with continued use,
they may induce tolerance and/or hyperalgesia, which limits therapeutic efficacy. The human …