Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Neuropathology underlying clinical variability in patients with synucleinopathies

GM Halliday, JL Holton, T Revesz, DW Dickson - Acta neuropathologica, 2011 - Springer
Abnormal aggregates of the synaptic protein, α-synuclein, are the dominant pathology in
syndromes known as the synucleinopathies. The cellular aggregation of the protein occurs …

When DLB, PD, and PSP masquerade as MSA: an autopsy study of 134 patients

S Koga, N Aoki, RJ Uitti, JA Van Gerpen, WP Cheshire… - Neurology, 2015 - AAN Enterprises
Objective: To determine ways to improve diagnostic accuracy of multiple system atrophy
(MSA), we assessed the diagnostic process in patients who came to autopsy with …

Second consensus statement on the diagnosis of multiple system atrophy

S Gilman, GK Wenning, PA Low, DJ Brooks… - Neurology, 2008 - AAN Enterprises
Background: A consensus conference on multiple system atrophy (MSA) in 1998
established criteria for diagnosis that have been accepted widely. Since then, clinical …

The natural history of multiple system atrophy: a prospective European cohort study

GK Wenning, F Geser, F Krismer, K Seppi… - The lancet …, 2013 - thelancet.com
Background Multiple system atrophy (MSA) is a fatal and still poorly understood
degenerative movement disorder that is characterised by autonomic failure, cerebellar …

Natural history of multiple system atrophy in the USA: a prospective cohort study

PA Low, SG Reich, J Jankovic, CW Shults… - The Lancet …, 2015 - thelancet.com
Background Multiple system atrophy is a rare, fatal neurodegenerative disorder with
symptoms of autonomic failure plus parkinsonism, cerebellar ataxia, or both. We report …

Mesenchymal stromal cell therapies for neurodegenerative diseases

NP Staff, DT Jones, W Singer - Mayo Clinic Proceedings, 2019 - Elsevier
Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …

Multiple system atrophy: an update

N Stefanova, P Bücke, S Duerr, GK Wenning - The Lancet Neurology, 2009 - thelancet.com
Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative
disorder that presents with autonomic failure in combination with parkinsonism or cerebellar …

Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy

RG Brown, L Lacomblez, BG Landwehrmeyer, T Bak… - Brain, 2010 - academic.oup.com
This article reports the severity and profile of neuropsychological impairment on a prevalent
cohort of patients with a clinical diagnosis of either multiple system atrophy (n= 372) or …

Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry

M Köllensperger, F Geser, JP Ndayisaba… - Movement …, 2010 - Wiley Online Library
Multiple system atrophy (MSA) is a Parkinson's Disease (PD)‐like α‐synucleinopathy
clinically characterized by dysautonomia, parkinsonism, cerebellar ataxia, and pyramidal …