Quantitative genetic studies (ie, twin and adoption studies) suggest that genetic influences
contribute substantially to the development of attention deficit hyperactivity disorder (ADHD) …

The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …

Attention-deficit hyperactivity disorder (ADHD) has been shown to be familial and heritable,
in previous studies. As with most psychiatric disorders, examination of pedigrees has not …

In vivo availability of striatal dopamine transporter (DAT) protein has been reported to be
reduced among alcoholics, and allelic variation of the DAT gene (SLC6A3) has been …

Methylphenidate is a commonly used medication in the United States. This central nervous
system stimulant has a mechanism of action distinct from that of amphetamine. The Food …

In humans, dopamine neurotransmission is influenced by functional polymorphisms in the
dopamine transporter (DAT 1) and catechol-O-methyltransferase (COMT) genes. Here, we …

The human dopamine transporter (DAT1) gene contains a variable number of tandem
repeats (VNTR) in its 3′-untranslated region (UTR). The linkage and association between …

Human aggression/impulsivity-related traits have a complex background that is greatly
influenced by genetic and non-genetic factors. The relationship between aggression and …

Individual differences in traits such as impulsivity involve high reward sensitivity and are
associated with risk for substance use disorders. The ventral striatum (VS) has been widely …

The authors measured food reinforcement, polymorphisms of the dopamine D 2 receptor
(DRD 2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese …