Epigenetics and signaling pathways in glaucoma
AC Gauthier, J Liu - BioMed research international, 2017 - Wiley Online Library
Glaucoma is the most common cause of irreversible blindness worldwide. This
neurodegenerative disease becomes more prevalent with aging, but predisposing genetic …
neurodegenerative disease becomes more prevalent with aging, but predisposing genetic …
MicroRNAs in glaucoma and neurodegenerative diseases
M Molasy, A Walczak, J Szaflik, JP Szaflik… - Journal of human …, 2017 - nature.com
MicroRNAs (miRNAs) constitute a class of short, non-coding RNAs, which have important
role in post-transcriptional regulation of genes expression by base-pairing with their target …
role in post-transcriptional regulation of genes expression by base-pairing with their target …
Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma
Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness
worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 …
worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 …
Identification of candidate miRNA biomarkers for glaucoma
AG Hindle, R Thoonen, JV Jasien… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: Glaucoma, a leading cause of blindness worldwide, often remains undetected until
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
irreversible vision loss has occurred. Treatments focus on lowering intraocular pressure …
The FOXC1/FBP1 signaling axis promotes colorectal cancer proliferation by enhancing the Warburg effect
Aberrant expression of Forkhead box (FOX) transcription factors plays vital roles in
carcinogenesis. However, the function of the FOX family member FOXC1 in maintenance of …
carcinogenesis. However, the function of the FOX family member FOXC1 in maintenance of …
miRNAs and genes involved in the interplay between ocular hypertension and primary open-angle glaucoma. Oxidative stress, inflammation, and apoptosis networks
J Raga-Cervera, JM Bolarin, JM Millan… - Journal of Clinical …, 2021 - mdpi.com
Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more
than 100 million people worldwide, with primary open angle glaucoma (POAG) being the …
than 100 million people worldwide, with primary open angle glaucoma (POAG) being the …
GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans
KS Nair, C Srivastava, RV Brown, S Koli… - Nature …, 2021 - nature.com
Chronically elevated intraocular pressure (IOP) is the major risk factor of primary open-angle
glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM) …
glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM) …
Roles of miR-204 in retinal development and maintenance
A Bereimipour, H Najafi, ES Mirsane, S Moradi… - Experimental Cell …, 2021 - Elsevier
The retina is the innermost part of the eye of most vertebrates and it is essential for vision.
The development, maintenance, and function of this laminated structure is tightly regulated …
The development, maintenance, and function of this laminated structure is tightly regulated …
[HTML][HTML] Genotype-phenotype association of PITX2 and FOXC1 in Axenfeld-Rieger syndrome
L Zhou, X Wang, J An, Y Zhang, M He… - Experimental Eye …, 2023 - Elsevier
PITX2 and FOXC1 are the most common pathogenic genes associated with Axenfeld-Rieger
syndrome (ARS). In this study, we aimed to explore the variation spectrum of PITX2 and …
syndrome (ARS). In this study, we aimed to explore the variation spectrum of PITX2 and …