A review of regional limb perfusion for distal limb infections in the horse

SA Biasutti, E Cox, LB Jeffcott… - Equine Veterinary …, 2021 - Wiley Online Library
Regional limb perfusion (RLP) is a technique widely used for the treatment of limb infections
in horses. The objective is to deliver high concentrations of an antimicrobial to a focal region …

[HTML][HTML] Effects of regional limb perfusion technique on concentrations of antibiotic achieved at the target site: A meta-analysis

LE Redding, EJ Elzer, KF Ortved - Plos one, 2022 - journals.plos.org
Intravenous regional limb perfusions (RLP) are widely used in equine medicine to treat
distal limb infections, including synovial sepsis. RLPs are generally deemed successful if the …

The effect of perfusate volume on amikacin concentration in the metacarpophalangeal joint following cephalic regional limb perfusion in standing horses

GL Oreff, R Dahan, AJ Tatz, T Raz, M Britzi… - Veterinary …, 2016 - Wiley Online Library
Objective To determine the influence of 3 perfusate volumes on amikacin concentration in
the metacarpophalangeal joint following cephalic regional limb perfusion (RLP) in standing …

Medical therapy in equine wound management

RR Hanson - Veterinary Clinics: Equine Practice, 2018 - vetequine.theclinics.com
The primary objective for the medical management of wounds is preventing infection and
creating an optimum environment for wound healing with the reestablishment of an …

[PDF][PDF] Regional limb perfusion in horses

G Kelmer - The Veterinary Record, 2016 - researchgate.net
REGIONAL limb perfusion (RLP) is a wellknown method for treating and preventing distal
limb infection, which significantly decreases morbidity and mortality associated with trauma …

Intravenous and intraosseous regional limb perfusion of ceftiofur sodium in an avian model

SE Knafo, JE Graham, BA Barton - American Journal of …, 2019 - Am Vet Med Assoc
OBJECTIVE To assess whether IV regional limb perfusion (IVRLP) and intraosseous
regional limb perfusion (IORLP) of ceftiofur sodium resulted in clinically relevant drug …

Determination of marbofloxacin in plasma and synovial fluid by ultrafiltration followed by HPLC–MS/MS

C Montesano, R Curini, M Sergi… - … of Pharmaceutical and …, 2016 - Elsevier
Abstract A rapid LC–MS/MS method for the determination of marbofloxacin in plasma and
synovial fluid is presented in this study. The method uses a rapid sample preparation which …

Meropenem synovial fluid concentrations after intravenous regional limb perfusion in standing horses

RL Fontenot, VC Langston, JA Zimmerman… - Veterinary …, 2018 - Wiley Online Library
Objective To determine meropenem concentrations in radiocarpal (RC) joint fluid and
plasma after intravenous regional limb perfusion (IVRLP). Study design In vivo experimental …

Pharmacokinetics of ampicillin-sulbactam in serum and synovial fluid samples following regional intravenous perfusion in the distal portion of a hind limb of adult cattle

SM Depenbrock, KM Simpson… - American journal of …, 2017 - Am Vet Med Assoc
OBJECTIVE To describe concentration-over-time data for ampicillin and sulbactam in the
digital and systemic circulations and synovial fluid (SYN) of cattle following a single injection …

Management of severely infected wounds

JA Orsini, YA Elce, B Kraus - Equine wound management, 2016 - Wiley Online Library
When managing serious wound infections in horses, it is important to consider the wound's
entire ecology, including the source and extent of contamination, the presence of bacterial …