This review summarizes the progress in the fluorination and fluoroalkylation of electron‐rich
systems with diverse fluorine (F) and fluoroalkyl (Rfn) reagents employing hypervalent …

Covering: 2011 to 2021 Trifluoromethyl (CF3)-modified natural products have attracted
increasing interest due to their magical effect in binding affinity and/or drug metabolism and …

Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-
CF3+ OTf–) as a novel trifluoromethylating reagent, which is conveniently accessible in a …

As one of the most powerful trifluoromethylation reagents,(trifluoromethyl) trimethylsilane
(TMSCF3) has been widely used for the synthesis of fluorine-containing molecules …

The radical 1, 2-difunctionalization reaction of alkynes has evolved into a versatile approach
to multisubstituted alkylenes. However, robust catalytic strategies to perform carboamination …

An electrochemical methodology for the Minisci-type trifluoromethylation of electron-deficient
heterocycles mediated by cheap and easily available bromide ions has been developed. By …

A ruthenium (II)-catalyzed C–H activation/annulation reaction of benzoic acids and CF3-
imidoyl sulfoxonium ylides enabled by weak O-coordination has been achieved. A series of …

An efficient and practical strategy was developed to synthesize 1, 3, 4-triaryl-6-
trifluoromethylpyridones from CF3-imidoyl sulfoxonium ylides and cyclopropenones in good …

A fast and simple method for deoxyfluorination of carboxylic acids is presented. The protocol
employs commodity chemicals (PPh3, NBS, fluoride), affording products in excellent yields …

An efficient and straightforward three-component reaction of enamides, aryldiazonium
tetrafluoroborates, and 1, 4-diazabicyclo [2.2. 2] octane bis (sulfur dioxide)(DABSO) for the …