The use of the intoxicating cannabinoid delta‐8‐tetrahydrocannabinol (Δ8‐THC) has grown
rapidly over the last several years. There have been dozens of Δ8‐THC studies dating back …

Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

The endocannabinoid signaling system is a widespread, neuromodulatory system in brain
and is also widely utilized in the periphery to modulate metabolic functions and the immune …

Cannabis (Cannabis sativa) is the most widely used illicit drug in the world, with an
estimated 192 million users globally. The main psychoactive component of cannabis is (−) …

Recent pharmacogenomic/pharmacogenetic (PGx) studies have disclosed important roles
for drug transporters in the human body. Changes in the functions of drug transporters due …

Although the application of medical marijuana and cannabinoid drugs is controversial, it is a
part of modern-day medicine. The list of diseases in which cannabinoids are promoted as a …

Cannabis and related compounds have created significant research interest as a promising
therapy in many disorders. However, the individual therapeutic effects of cannabinoids and …

Background: Cannabinoid hyperemesis syndrome (CHS) is a diagnosis of exclusion with
intractable nausea, cyclic vomiting, abdominal pain, and hot bathing behavior associated …

Designer drugs belong to a group of legally or illegally produced substances that are
structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs …

Background Genetic variability may influence methadone metabolism, dose requirements,
and risk of relapse. Objectives To determine whether the CYP2B6* 6 or ABCB1 (rs1045642) …