Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications
W Danysz, CG Parsons - Pharmacological reviews, 1998 - ASPET
Since the finding by Johnson and Ascher (1987) demonstrating that glycine enhances
electrophysiological responses mediated by N-methyl-D-aspartate (NMDA) b
electrophysiological responses mediated by N-methyl-D-aspartate (NMDA) b
Quinoxalines, Volume 61, Spplement 2
DJ Brown, EC Taylor, JA Ellman - 2004 - books.google.com
This volume in the Chemistry of Heterocyclic Compounds series presents a comprehensive
review of the quinoxaline literature from 1975 to the present (2002), updating Volumes 5 and …
review of the quinoxaline literature from 1975 to the present (2002), updating Volumes 5 and …
Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists
A major issue in designing drugs as antagonists at the glycine site of the NMDA receptor has
been to achieve good in vivo activity. A series of 4-hydroxyquinolone glycine antagonists …
been to achieve good in vivo activity. A series of 4-hydroxyquinolone glycine antagonists …
Synthesis, Antimicrobial and Antibiofilm Activities, and Molecular Docking Investigations of 2-(1H-Indol-3-yl)-1H-benzo[d]imidazole Derivatives
EY Mendogralo, LY Nesterova, ER Nasibullina… - Molecules, 2023 - mdpi.com
The treatment of many bacterial and fungal infections remains a problem due to increasing
antibiotic resistance and biofilm formation by pathogens. In the present article, a …
antibiotic resistance and biofilm formation by pathogens. In the present article, a …
Synthesis, ionisation potentials and electron affinities of hexaazatrinaphthylene derivatives
S Barlow, Q Zhang, BR Kaafarani… - … A European Journal, 2007 - Wiley Online Library
Several hexaazatrinaphthylene derivatives and a tris (thieno) hexaazatriphenylene
derivative have been synthesised by reaction of the appropriate diamines with …
derivative have been synthesised by reaction of the appropriate diamines with …
A review on multipurpose potential of bioactive heterocycle quinoxaline
In last few decades, nitrogen‐containing heterocycles have maintained their status as an
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …
Structure−Activity Relationships of 1,4-Dihydro-(1H,4H)-quinoxaline-2,3-diones as N-Methyl-d-aspartate (Glycine Site) Receptor Antagonists. 1. Heterocyclic …
MJ Fray, DJ Bull, CL Carr, ECL Gautier… - Journal of medicinal …, 2001 - ACS Publications
A series of 6, 7-dichloro-1, 4-dihydro-(1H, 4H)-quinoxaline-2, 3-diones (1− 17) were
prepared in which the 5-position substituent was a heterocyclylmethyl or 1-(heterocyclyl)-1 …
prepared in which the 5-position substituent was a heterocyclylmethyl or 1-(heterocyclyl)-1 …
Antinociceptive effects of NMDA and non-NMDA receptor antagonists in the tail flick test in mice
K Lutfy, SX Cai, RM Woodward, E Weber - Pain, 1997 - Elsevier
Inhibition of spinal glutamate receptors induces antinociceptive effects in numerous animal
models of pain. The present study compares the effects of intrathecally administered N …
models of pain. The present study compares the effects of intrathecally administered N …
Preventing neuronal degeneration in Alzheimer's disease
JW Olney, NB Farber - US Patent 5,877,173, 1999 - Google Patents
US5877173A - Preventing neuronal degeneration in Alzheimer's disease - Google Patents
US5877173A - Preventing neuronal degeneration in Alzheimer's disease - Google Patents …
US5877173A - Preventing neuronal degeneration in Alzheimer's disease - Google Patents …
Long‐Wavelength‐Absorbing and‐Emitting Carbostyrils with High Fluorescence Quantum Yields
G Uray, KS Niederreiter, F Belaj… - Helvetica Chimica …, 1999 - Wiley Online Library
Synthesis, absorption and fluorescence spectra, as well as quantum yields of a series of
donor‐acceptor‐substituted carbostyrils (= quinolin‐2 (1H)‐ones), are reported …
donor‐acceptor‐substituted carbostyrils (= quinolin‐2 (1H)‐ones), are reported …