Since the finding by Johnson and Ascher (1987) demonstrating that glycine enhances
electrophysiological responses mediated by N-methyl-D-aspartate (NMDA) b

This volume in the Chemistry of Heterocyclic Compounds series presents a comprehensive
review of the quinoxaline literature from 1975 to the present (2002), updating Volumes 5 and …

A major issue in designing drugs as antagonists at the glycine site of the NMDA receptor has
been to achieve good in vivo activity. A series of 4-hydroxyquinolone glycine antagonists …

The treatment of many bacterial and fungal infections remains a problem due to increasing
antibiotic resistance and biofilm formation by pathogens. In the present article, a …

Several hexaazatrinaphthylene derivatives and a tris (thieno) hexaazatriphenylene
derivative have been synthesised by reaction of the appropriate diamines with …

In last few decades, nitrogen‐containing heterocycles have maintained their status as an
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …

A series of 6, 7-dichloro-1, 4-dihydro-(1H, 4H)-quinoxaline-2, 3-diones (1− 17) were
prepared in which the 5-position substituent was a heterocyclylmethyl or 1-(heterocyclyl)-1 …

Inhibition of spinal glutamate receptors induces antinociceptive effects in numerous animal
models of pain. The present study compares the effects of intrathecally administered N …

US5877173A - Preventing neuronal degeneration in Alzheimer's disease - Google Patents
US5877173A - Preventing neuronal degeneration in Alzheimer's disease - Google Patents …

Synthesis, absorption and fluorescence spectra, as well as quantum yields of a series of
donor‐acceptor‐substituted carbostyrils (= quinolin‐2 (1H)‐ones), are reported …