Background The treatment of neuropathic pain remains a major unmet need that the
development of personalized and refined treatment strategies may contribute to address …

Chronic pain is a constantly recurring and persistent illness, presenting a formidable
healthcare challenge for patients and physicians alike. Current first‐line analgesics offer …

Aim This study aims to profile migraine patients according clinical and psychophysical
characteristics. Method In this observational study, two cohorts of migraine patients …

Although the prevalence of cancer pain is 47% after treatment, cancer pain is often
underestimated, and many patients are undertreated. The complexity of cancer pain …

Pain is one of the most frequent and persistent side effects of breast cancer treatment.
Besides pain, breast cancer survivors (BCS) are prone to experience a myriad of other signs …

The artemin-GFRα3 signaling pathway has been implicated in various painful conditions
including migraine, cold allodynia, hyperalgesia, inflammatory bone pain, and mouse knees …

Purpose: Altered pain facilitatory and inhibitory mechanisms have been recognized as an
important manifestation in patients with chronic pain, and quantitative sensory testing (QST) …

Objective Osteoarthritis (OA) drug development is hampered by a number of challenges.
One of the main challenges is the apparent discordance between pain and structure, which …

Introduction Currently, examination of migraine patients relies on a clinical interview
investigating symptoms characteristics. Despite this, to help identify distinct migraine …

Background Facilitatory and inhibitory conditioned pain modulation (CPM) responses are
observed in healthy volunteers and chronic pain patients, but the clinical implications for …