Riluzole for the treatment of amyotrophic lateral sclerosis

Y Saitoh, Y Takahashi - Neurodegenerative disease management, 2020 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by
the death of motor neurons. Riluzole is a benzothiazole derivative that blocks glutamatergic …

Medications on hypertension, hyperlipidemia, diabetes, and risk of amyotrophic lateral sclerosis: A systematic review and meta-analysis

N Hu, H Ji - Neurological Sciences, 2022 - Springer
Objective To investigate the association between the use of common medications on
hypertension, hyperlipidemia, diabetes, and the risk of amyotrophic lateral sclerosis (ALS) …

Ten years of riluzole use in a tertiary ALS clinic

A Geronimo, RM Albertson, J Noto… - Muscle & nerve, 2022 - Wiley Online Library
Abstract Introduction/Aims Riluzole is a glutamate inhibitor approved for the treatment of
amyotrophic lateral sclerosis (ALS). There are scant data on factors associated with riluzole …

[HTML][HTML] A cost-effectiveness framework for amyotrophic lateral sclerosis, applied to riluzole

NJ Thakore, EP Pioro, BL Udeh, BR Lapin, IL Katzan - Value in Health, 2020 - Elsevier
Objectives Reexamine cost-effectiveness of riluzole in the treatment of amyotrophic lateral
sclerosis (ALS) in light of recent advances in disease staging and understanding of stage …

Advances in disease-modifying pharmacotherapies for the treatment of amyotrophic lateral sclerosis

R Hergesheimer, D Lanznaster, P Vourc'h… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction To date, riluzole and edaravone are the only two drugs that have successfully
passed clinical trials for the treatment of Amyotrophic Lateral Sclerosis (ALS). Unfortunately …

The effectiveness of nonsteroidal anti-inflammatory drugs and acetaminophen in reduce the risk of amyotrophic lateral sclerosis? A meta-analysis

MC Chang, SG Kwak, JS Park, D Park - Scientific reports, 2020 - nature.com
To test the hypothesis that aspirin, non-aspirin nonsteroidal anti-infammatory drugs (NA-
NSAIDs), or acetaminophen can reduce the risk of ALS, we conducted a systematic review …

[HTML][HTML] Occupational therapy using a robotic-assisted glove ameliorates finger dexterity and modulates functional connectivity in amyotrophic lateral sclerosis

I Yamakawa, A Yamada, Y Sonoda, K Wakita… - Journal of Clinical …, 2023 - Elsevier
Introduction Although rehabilitation is recommended for amyotrophic lateral sclerosis (ALS),
improvement of functional decline has hardly been achieved. We investigated the effect of …

[HTML][HTML] Mapping of critical events in disease progression through binary classification: Application to amyotrophic lateral sclerosis

ÖO Dalgıç, H Wu, FS Erenay, MY Sir, OY Özaltın… - Journal of Biomedical …, 2021 - Elsevier
Background The progression of many degenerative diseases is tracked periodically using
scales evaluating functionality in daily activities. Although estimating the timing of critical …

[HTML][HTML] Disease‐modifying pharmacological treatments for amyotrophic lateral sclerosis/motor neuron disease: an overview of intervention reviews

R Balendra, RW Orrell, N Pearce… - The Cochrane Database …, 2023 - ncbi.nlm.nih.gov
Disease‐modifying pharmacological treatments for amyotrophic lateral sclerosis/motor neuron
disease: an overview of intervention reviews - PMC Back to Top Skip to main content NIH NLM …

Continuity of treatment in ALS: Benefits and challenges of maintaining riluzole over the course of the disease

V Silani - Journal of the Neurological Sciences, 2024 - Elsevier
Continuity of treatment in ALS: Benefits and challenges of maintaining riluzole over the course
of the disease - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …