Machine learning approaches for influenza A virus risk assessment identifies predictive correlates using ferret model in vivo data

TJ Kieran, X Sun, TR Maines, JA Belser - Communications Biology, 2024 - nature.com
In vivo assessments of influenza A virus (IAV) pathogenicity and transmissibility in ferrets
represent a crucial component of many pandemic risk assessment rubrics, but few …

COVID-19 virus mutation prediction with LSTM and attention mechanisms

M Burukanli, N Yumuşak - The Computer Journal, 2024 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2, is an emerging and rapidly spreading type of coronavirus. One of …

Computational methods to analyze RNA data for human diseases

P Ding, M Zeng, R Yin - Frontiers in Genetics, 2023 - frontiersin.org
RNA, as a type of nucleic acid, forms one of the four fundamental macromolecules crucial for
all known life forms. Unlike DNA (Deoxyribonucleic Acid), which typically serves as the …

StackGridCov: a robust stacking ensemble learning-based model integrated with GridSearchCV hyperparameter tuning technique for mutation prediction of COVID-19 …

M Burukanli, N Yumuşak - Neural Computing and Applications, 2024 - Springer
The emergence of the coronavirus disease 2019 (COVID-19) pandemic has caused great
fear and panic around the world. In order to fight the COVID-19 virus, countries have had to …

TfrAdmCov: a robust transformer encoder based model with Adam optimizer algorithm for COVID-19 mutation prediction

M Burukanli, N Yumuşak - Connection Science, 2024 - Taylor & Francis
The development of vaccines and drugs is very important in combating the coronavirus
disease 2019 (COVID-19) virus. The effectiveness of these developed vaccines and drugs …

CLCAP: Contrastive learning improves antigenicity prediction for influenza A virus using convolutional neural networks

R Yin, B Ye, J Bian - Methods, 2023 - Elsevier
Influenza viruses are detected year-round over the world and the viruses will usually
circulate during fall and winter, causing the seasonal flu. The growing novel variants of …

Jupytope: computational extraction of structural properties of viral epitopes

S Rashid, TA Ng, CK Kwoh - Briefings in Bioinformatics, 2022 - academic.oup.com
Epitope residues located on viral surface proteins are of immense interest in immunology
and related applications such as vaccine development, disease diagnosis and drug design …