Pharmacology of heparin and related drugs: an update

J Hogwood, B Mulloy, R Lever, E Gray, CP Page… - Pharmacological …, 2023 - Elsevier
Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

Herpesvirus‐Mimicking DNAzyme‐Loaded Nanoparticles as a Mitochondrial DNA Stress Inducer to Activate Innate Immunity for Tumor Therapy

X Zhao, Y Wang, W Jiang, Q Wang, J Li… - Advanced …, 2022 - Wiley Online Library
Virus‐based immunotherapy is a promising approach to treat tumor. Closely mimicking the
structure and sequential infection processes of natural viruses is highly desirable for …

The importance of glycans of viral and host proteins in enveloped virus infection

Y Li, D Liu, Y Wang, W Su, G Liu, W Dong - Frontiers in Immunology, 2021 - frontiersin.org
Animal viruses are parasites of animal cells that have characteristics such as heredity and
replication. Viruses can be divided into non-enveloped and enveloped viruses if a lipid …

Anti-viral triterpenes: a review

P Darshani, S Sen Sarma, AK Srivastava… - Phytochemistry …, 2022 - Springer
Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

Natural products as potential lead compounds to develop new antiviral drugs over the past decade

JH Zhao, YW Wang, J Yang, ZJ Tong, JZ Wu… - European Journal of …, 2023 - Elsevier
Virus infection has been one of the main causes of human death since the ancient times.
Even though more and more antiviral drugs have been approved in clinic, long-term use can …

Alkaloids as potential antivirals. A comprehensive review

S Faisal, SL Badshah, B Kubra, AH Emwas… - Natural Products and …, 2023 - Springer
Alkaloids are a diverse group of natural phytochemicals. These phytochemicals in plants
provide them protection against pests, and herbivorous organisms and also control their …

Heparan sulfate proteoglycans in viral infection and treatment: a special focus on SARS-CoV-2

V De Pasquale, MS Quiccione, S Tafuri… - International Journal of …, 2021 - mdpi.com
Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

Developments in vaccination for herpes simplex virus

R Krishnan, PM Stuart - Frontiers in microbiology, 2021 - frontiersin.org
Herpes simplex virus (HSV) is an alpha herpes virus, with two subtypes: HSV-1 and HSV-2.
HSV is one of the most prevalent sexually transmitted infections. It is the cause of severe …

SARS-CoV-2 cellular entry is independent of the ACE2 cytoplasmic domain signaling

T Karthika, J Joseph, VRA Das, N Nair, P Charulekha… - Cells, 2021 - mdpi.com
Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and-2
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …