Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting

EP Newcomer, SRS Fishbein, K Zhang, T Hink… - Mbio, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea,
despite the widespread implementation of contact precautions for patients with CDI. Here …

Comparative genome analyses of clinical and non-clinical Clostridioides difficile strains

MA Schüler, T Riedel, J Overmann, R Daniel… - Frontiers in …, 2024 - frontiersin.org
The pathogenic bacterium Clostridioides difficile is a worldwide health burden with
increasing morbidity, mortality and antibiotic resistances. Therefore, extensive research …

[HTML][HTML] Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain

Q Dong, S Harper, E McSpadden, SS Son, MM Allen… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) strains belonging to the epidemic BI/NAP1/027 (RT027)
group have been associated with increased transmissibility and disease severity. In addition …

Flagellar switch inverted repeat sequence variation impacts Clostridioides difficile RT027/MLST1 virulence

NTQ Nhu, H Lin, JK Sia, ES Snitkin, V Young… - bioRxiv, 2023 - biorxiv.org
The impact of Clostridioides difficile strain diversity on the severity of intestinal infection and
diarrhea remains unclear. The RT027/ST1 strain is highly prevalent and has been …

[PDF][PDF] Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting

N EP - … and Prevention of Antibiotic Resistant Organism …, 2023 - openscholarship.wustl.edu
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea,
despite the widespread implementation of contact precautions for patients with CDI. Here …