Folate is a dietary micronutrient essential to one-carbon metabolism. The World Health
Organisation recommends folic acid (FA) supplementation pre-conception and in early …

The rationale and importance of folic acid supplementation during pregnancy for fetal
congenital defect prevention are accepted worldwide. Moreover, a sufficient plasma …

The placenta is particularly susceptible to inflammation and oxidative stress, leading to
placental vascular dysfunction and placental insufficiency, which is associated with fetal …

Folic acid (FA) is a synthetic and highly stable version of folate, while 6S-5-
methyltetrahydrofolate is the predominant form of dietary folate in circulation and is used as …

Food fortification and increased vitamin intake have led to higher folic acid (FA) consumption
by many pregnant women. We showed that FA-supplemented diet in pregnant mice (fivefold …

Folate, also known as vitamin B9, facilitates the transfer of methyl groups among molecules,
which is crucial for amino acid metabolism and nucleotide synthesis. Adequate maternal …

Background Inadequate pregnancy cobalamin status has been associated with adverse
offspring metabolic health in Indian and Nepalese studies. Studies of pregnancy cobalamin …

Introduction The implications of folate deficiency in neuropsychiatric disorders were
demonstrated in numerous studies. Genetic deficiency in a key folate metabolism enzyme …

Folic acid plays an important role in the synthesis, repair, and methylation of
deoxyribonucleic acid (DNA). Currently, most studies have focused on the effects of …

Folic acid (FA) food fortification in Australia has resulted in a higher-than-expected intake of
FA during pregnancy. High FA intake is associated with increased insulin resistance and …