Bone fractures are the most common traumatic injuries in humans. The repair of bone
fractures is a regenerative process that recapitulates many of the biological events of …

Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Bone defect repair is a challenging clinical problem in musculoskeletal system, especially in
orthopaedic disorders such as steroid associated osteonecrosis (SAON). Magnesium (Mg) …

Large bone defects resulting from fractures and disease are a medical concern, being often
unable to heal spontaneously by the body's repair mechanisms. Bone tissue engineering …

Promoting bone regeneration and repairing defects are urgent and critical challenges in
orthopedic clinical practice. Research on bone substitute biomaterials is essential for …

Abstract 3D-printed composite scaffolds have emerged as an alternative to deal with existing
limitations when facing bone reconstruction. The aim of the study was to systematically …

Critical size bone defects are frequently caused by accidental trauma, oncologic surgery,
and infection. Distraction osteogenesis (DO) is a useful technique to promote the repair of …

Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

Steroid-associated osteonecrosis (SAON) often requires surgical core decompression (CD)
in the early stage for removal of necrotic bone to facilitate repair where bone grafts are …

Polyetheretherketone (PEEK) has been an alternative material for titanium in bone defect
repair, but its clinical application is limited by its poor osseointegration. In this study, a …