Members of the arginine–serine-rich protein family (SR proteins) are multifunctional RNA-
binding proteins that have emerged as key determinants for mRNP formation, identity and …

Ser/Arg-rich (SR) proteins are RNA-binding proteins known as constitutive and alternative
splicing (AS) regulators that regulate multiple aspects of the gene expression program …

Rationale: Excessive Ang II (angiotensin II) levels lead to a profibrotic and hypertrophic
milieu that produces deleterious remodeling and dysfunction in hypertension-associated …

BACKGROUND: Heart failure, characterized by cardiac remodeling, is associated with
abnormal epigenetic processes and aberrant gene expression. Here, we aimed to elucidate …

Background: Cardiac remodeling in heart failure involves macrophage-mediated immune
responses. Recent studies have shown that a PRR (pattern recognition receptor) called …

The mitochondrial transmembrane (TMEM) protein family has several essential
physiological functions. However, its roles in cardiomyocyte proliferation and cardiac …

Flesh quality is evaluated according to nutritional value and sensory quality.
Cinnamaldehyde (CIN) improves mammalian meat quality, but research relating this to …

Rationale: Previously, we identified the human cardiac long noncoding RNAs (lncRNAs)
profile in patients with dilated cardiomyopathy (DCM), among which ZNF593-AS, also …

The RNA isoform repertoire is regulated by splicing factor (SF) expression, and alterations in
SF levels are associated with disease. SFs contain ultraconserved poison exon (PE) …

Background: Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder. The
aim of the present investigation was to identify gene signature specific to T2DM. Methods …