An intricate relation exists between gene trees and species phylogenies, due to evolutionary
processes that act on the genes within and across the branches of the species phylogeny …

Conformational flexibility conferred though regions of intrinsic structural disorder allows
proteins to behave as dynamic molecules. While it is well-known that intrinsically disordered …

The evolutionary rates of protein-coding genes in an organism span, approximately, 3
orders of magnitude and show a universal, approximately log-normal distribution in a broad …

The P450 enzymes maintain a conserved P450 fold despite a considerable variation in
sequence. The P450 family even includes proteins that lack the single conserved cysteine …

Gene duplication is an important process in the functional divergence of genes and
genomes. Several processes have been described that lead to duplicate gene retention …

Whole-genome sequence data have revealed that numerous eukaryotic organisms derive
from distant polyploid ancestors, even when these same organisms are genetically and …

Background The number of species with completed genomes, including those with evidence
for recent whole genome duplication events has exploded. The recently sequenced Atlantic …

A clustering of all protein coding genes from the complete genomes of five tetrapod species
into gene families shows a clear deviation from the expected power-law distribution of gene …

Background Rupture of abdominal aortic aneurysm (rAAA) is a fatal event in the elderly.
Elevated blood pressure and weakening of vessel wall strength are major risk factors for this …

Background The vertebrate tetraspanin family has many features which make it suitable for
preserving the imprint of ancient sequence evolution and amenable for phylogenomic …