Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Plants as sources of new antimicrobials and resistance-modifying agents

AC Abreu, AJ McBain, M Simões - Natural product reports, 2012 - pubs.rsc.org
Covering: up to November 2011 Infections caused by multidrug-resistant bacteria are an
increasing problem due to the emergence and propagation of microbial drug resistance and …

Biosynthesis investigations of terpenoid, alkaloid, and flavonoid antimicrobial agents derived from medicinal plants

W Huang, Y Wang, W Tian, X Cui, P Tu, J Li, S Shi… - Antibiotics, 2022 - mdpi.com
The overuse of antibiotics in the past decades has led to the emergence of a large number
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …

Synergy research: approaching a new generation of phytopharmaceuticals

H Wagner, G Ulrich-Merzenich - Phytomedicine, 2009 - Elsevier
The longstanding, successful use of herbal drug combinations in traditional medicine makes
it necessary to find a rationale for the pharmacological and therapeutic superiority of many of …

Synergism between natural products and antibiotics against infectious diseases

S Hemaiswarya, AK Kruthiventi, M Doble - Phytomedicine, 2008 - Elsevier
Antibiotics have been effective in treating infectious diseases, but resistance to these drugs
has led to the emergence of new and the reemergence of old infectious diseases. One …

Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study

G Appendino, S Gibbons, A Giana… - Journal of natural …, 2008 - ACS Publications
Marijuana (Cannabis sativa) has long been known to contain antibacterial cannabinoids,
whose potential to address antibiotic resistance has not yet been investigated. All five major …

Efflux-mediated drug resistance in bacteria

XZ Li, H Nikaido - Drugs, 2004 - Springer
Drug resistance in bacteria, and especially resistance to multiple antibacterials, has
attracted much attention in recent years. In addition to the well known mechanisms, such as …

Bacterial efflux pump inhibitors from natural sources

M Stavri, LJV Piddock, S Gibbons - Journal of antimicrobial …, 2007 - academic.oup.com
The rapid spread of bacteria expressing multidrug resistance (MDR) has necessitated the
discovery of new antibacterials and resistance-modifying agents. Since the initial discovery …

Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms

M Simoes, RN Bennett, EAS Rosa - Natural product reports, 2009 - pubs.rsc.org
Covering: up to November 2008New sources of antimicrobial products need to be identified
due to the existence and constant evolution of resistant microorganisms and phenotypes …

Anti-staphylococcal plant natural products

S Gibbons - Natural product reports, 2004 - pubs.rsc.org
Covering: 1995 to 2003 The occurrence of vancomycin-resistant Staphylococcus aureus
(VRSA) and multidrug-resistant (MDR) strains of this organism necessitate the discovery of …