The role of machine learning and design of experiments in the advancement of biomaterial and tissue engineering research

G Al-Kharusi, NJ Dunne, S Little, TJ Levingstone - Bioengineering, 2022 - mdpi.com
Optimisation of tissue engineering (TE) processes requires models that can identify
relationships between the parameters to be optimised and predict structural and …

Regeneration of skeletal system with genipin crosslinked biomaterials

Z Wang, H Liu, W Luo, T Cai, Z Li… - Journal of Tissue …, 2020 - journals.sagepub.com
Natural biomaterials, such as collagen, gelatin, and chitosan, are considered as promising
candidates for use in tissue regeneration treatment, given their similarity to natural tissues …

MLATE: Machine learning for predicting cell behavior on cardiac tissue engineering scaffolds

S Rafieyan, E Vasheghani-Farahani… - Computers in Biology …, 2023 - Elsevier
Cardiovascular disease is one of the leading causes of mortality worldwide and is
responsible for millions of deaths annually. One of the most promising approaches to deal …

Evaluation of different crosslinking methods in altering the properties of extrusion-printed chitosan-based multi-material hydrogel composites

S Liu, H Zhang, T Ahlfeld, D Kilian, Y Liu… - Bio-Design and …, 2023 - Springer
Three-dimensional printing technologies exhibit tremendous potential in the advancing
fields of tissue engineering and regenerative medicine due to the precise spatial control …

[HTML][HTML] AI-driven 3D bioprinting for regenerative medicine: from bench to bedside

Z Zhang, X Zhou, Y Fang, Z Xiong, T Zhang - Bioactive Materials, 2025 - Elsevier
In recent decades, 3D bioprinting has garnered significant research attention due to its
ability to manipulate biomaterials and cells to create complex structures precisely. However …

A comprehensive review on genipin: An efficient natural cross-linker for biopolymers

MI Wahba - Polymer Bulletin, 2024 - Springer
Cross-linkers are pivotal to meliorate the attributes of the biopolymers, which are exploited in
the biomedical industries, and also those intended as packaging supplies. Genipin (GN) is …

Aligned ice templated biomaterial strategies for the musculoskeletal system

F Diaz, N Forsyth, AR Boccaccini - Advanced Healthcare …, 2023 - Wiley Online Library
Aligned pore structures present many advantages when conceiving biomaterial strategies
for treatment of musculoskeletal disorders. Aligned ice templating (AIT) is one of the many …

Application of artificial neural networks to predict Young's moduli of cartilage scaffolds: an in-vitro and micromechanical study

A Khalvandi, S Saber-Samandari, MM Aghdam - Biomaterials Advances, 2022 - Elsevier
In this study, four-phase Gelatin-Polypyrrole-Akermanite-Magnetite scaffolds were fabricated
and analyzed using in-vitro tests and numerical simulations. Such scaffolds contained …

Gelatin hydrogel reinforced by graphene oxide grafted chitosan for cartilage tissue engineering application

V Nazar, M Kashi, M Haghbin Nazarpak… - … Journal of Polymeric …, 2023 - Taylor & Francis
Various methods, such as cross-linking and incorporation of nanoparticles, enhance
hydrogels' physical and mechanical properties. Therefore, in the present research, gelatin …

Engineered approach coupled with machine learning in biofabrication of patient-specific nerve guide conduits-Review

DV Krishna, MR Sankar - Bioprinting, 2023 - Elsevier
Nervous system plays a dynamic role in communicating information from the brain to body
parts through central and peripheral nerves. Significant destruction to the nerve system …