Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to
its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide …

Hypoxia not only promotes tumor metastasis but also strengthens tumor resistance to
therapies that demand the involvement of oxygen, such as radiation therapy and …

Reactive oxygen species (ROS)-based dynamic cancer therapies are therapeutic modalities
of endogenous/exogenous-responsive intratumoral ROS generation, including …

Premature leakage of photosensitizer (PS) from nanocarriers significantly reduces the
accumulation of PS within a tumor, thereby enhancing nonspecific accumulation in normal …

The advancements in nanotechnology have created multifunctional nanomaterials aimed at
enhancing diagnostic accuracy and treatment efficacy for cancer. However, the ability to …

Photodynamic therapy (PDT) is a promising treatment modality for cancer management. So
far, most PDT studies have focused on delivery of photosensitizers to tumors. O2, another …

Smart/intelligent contrast agent candidates for MRI based on Mn (II) ion are rare, as it usually
forms labile complexes with polyaminocarboxylate-type ligands. Here, we report the first …