The repurposed ACE2 inhibitors: SARS-CoV-2 entry blockers of Covid-19
The highly infectious disease COVID-19 is induced by SARS-coronavirus 2 (SARS-CoV-2),
which has spread rapidly around the globe and was announced as a pandemic by the World …
which has spread rapidly around the globe and was announced as a pandemic by the World …
Counter-regulatory renin-angiotensin system in hypertension: Review and update in the era of COVID-19 pandemic
H Chen, J Peng, T Wang, J Wen, S Chen… - Biochemical …, 2023 - Elsevier
Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …
Molecular modelling identification of phytocompounds from selected African botanicals as promising therapeutics against druggable human host cell targets of SARS …
Abstract The coronavirus disease 2019 (COVID-19), caused by the Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly pathogenic and …
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly pathogenic and …
ACE2/ANG-(1-7)/Mas receptor axis activation prevents inflammation and improves cognitive functions in streptozotocin induced rat model of Alzheimer's disease-like …
V Tiwari, J Singh, P Tiwari, S Chaturvedi… - European Journal of …, 2023 - Elsevier
Activation of the renin-angiotensin system (RAS), by Angiotensin converting
enzyme/Angiotensin II/Angiotensin receptor-1 (ACE/Ang II/AT1 R) axis elicits amyloid …
enzyme/Angiotensin II/Angiotensin receptor-1 (ACE/Ang II/AT1 R) axis elicits amyloid …
A mimetic peptide of ACE2 protects against SARS-CoV-2 infection and decreases pulmonary inflammation related to COVID-19
EH Oliveira, AC Monteleone-Cassiano, L Tavares… - Antiviral Research, 2024 - Elsevier
Since human angiotensin-converting enzyme 2 (ACE2) serves as a primary receptor for
SARS-CoV-2, characterizing ACE2 regions that allow SARS-CoV-2 to enter human cells is …
SARS-CoV-2, characterizing ACE2 regions that allow SARS-CoV-2 to enter human cells is …
SARS-CoV-2 infection and ACE2 inhibition
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread across the
world and it is still a major public health concern [1]. SARS-CoV-2 was found to share …
world and it is still a major public health concern [1]. SARS-CoV-2 was found to share …
In silico approach for the evaluation of the potential antiviral activity of extra virgin olive oil (EVOO) bioactive constituents oleuropein and oleocanthal on spike …
EG Geromichalou, GD Geromichalos - Molecules, 2022 - mdpi.com
Since there is an urgent need for novel treatments to combat the current coronavirus disease
2019 (COVID-19) pandemic, in silico molecular docking studies were implemented as an …
2019 (COVID-19) pandemic, in silico molecular docking studies were implemented as an …
Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?
A Berenyiova, I Bernatova, A Zemancikova, M Drobna… - Biomedicines, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects host cells through
angiotensin-converting enzyme 2 (ACE2). Concurrently, the product of ACE2 action …
angiotensin-converting enzyme 2 (ACE2). Concurrently, the product of ACE2 action …
Comparison of the unbinding process of RBD-ACE2 complex between SARS-CoV-2 variants (Delta, Delta plus, and Lambda): A steered molecular dynamics …
M Abidi, R Soheilifard, RH Ghasemi - Molecular Simulation, 2022 - Taylor & Francis
ABSTRACT The Delta and Lambda SARS-CoV-2 variants are characterised with the double
mutations T478K/L452R, and F490S/L452Q, respectively, in their receptor binding domains …
mutations T478K/L452R, and F490S/L452Q, respectively, in their receptor binding domains …
In Silico Docking to Explore the Coronavirus-2 ACE2 Inhibitor Potential in Brown Seaweed Padina sp. from Morotai Island, North Maluku, Indonesia.
Efforts to explore new sources of antivirals for coronavirus-2 from abundant marine natural
materials are highly encouraged. The study aimed to explore the potential compounds of …
materials are highly encouraged. The study aimed to explore the potential compounds of …